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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
human polymorphonuclear leukocyte elastase
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "human polymorphonuclear leukocyte elastase" in MCE Product Catalog:
Cat. No.: HY-P4126
CAS No.: 113277-37-5
Cat. No.: HY-120876
CAS No.: 127063-08-5
Target:
Research Areas:
L-680833 is a monocyclic β-lactam inhibitor of human polymorphonuclear leukocyte elastase (PMNE) inhibitor. L-680833 can be used for the study of PMNE-damaged tissue diseases .
Cat. No.: HY-106899
CAS No.: 135947-75-0
Research Areas:
MK 287 is a potent, selective and orally active antagonist of platelet-activating factor receptor (PAFR). MK 287 can inhibit [3H]C18-PAF binding to human platelet, polymorphonuclear leukocyte (PMN) and lung membranes with K1 values of 6.1, 3.2, and 5.49 nM, respectively. MK 287 can inhibit PAF-induced aggregation of platelets in plasma or gel-filtered platelets and elastase release from PMNs with ED50 values of 56, 1.5 and 4.4 nM. MK 287 can be used for the research of cardiovascular disease, such as thrombosis .
Cat. No.: HY-118261
CAS No.: 119742-06-2
Target:
Research Areas:
L 659286 is an inhibitor of human polymorphonuclear leukocyte elastase (PMN elastase) (Ki=0.4 μM). Intratracheal injection of L 659286 can induce lung injury in hamsters.
Cat. No.: HY-106899A
CAS No.: 143445-03-8
Synonyms: (rel)-L-680573
Research Areas:
(rel)-MK 287 ((rel)-L-680573) is a relative configuration of MK 287. MK 287 is a potent, selective and orally active antagonist of platelet-activating factor receptor (PAFR). MK 287 can inhibit [3H]C18-PAF binding to human platelet, polymorphonuclear leukocyte (PMN) and lung membranes with K1 values of 6.1, 3.2, and 5.49 nM, respectively. MK 287 can inhibit PAF-induced aggregation of platelets in plasma or gel-filtered platelets and elastase release from PMNs with ED50 values of 56, 1.5 and 4.4 nM. MK 287 can be used for the research of cardiovascular disease, such as thrombosis .
Cat. No.: HY-117811
CAS No.: 143490-81-7
Synonyms: L-680574
Research Areas:
(R,R)-MK 287 (L-680574) is a tetrahydrofuran derivative that potently inhibits the binding of [3H]C18-PAF to human platelets, polymorphonuclear leukocytes (PMNs), and lung membranes with Ki values of 6.1, 3.2, and 5.49 nM, respectively. (R,R)-MK 287 potently and selectively inhibits PAF-induced platelet aggregation (ED50=56 nM) and elastase release from PMNs (ED50=4.4 nM). (R,R)-MK 287 inhibits PAF-induced lethality in mice (ED50=0.8 mg/kg, po) and PAF-induced bronchospasm in guinea pigs (ED50=0.18 mg/kg) .
Cat. No.: HY-P72179
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Bone marrow serine protease; ELA2; ELANE; elastase 2; elastase 2 neutrophil; elastase neutrophil expressed; elastase-2; ELNE_human; GE; Granulocyte derived elastase; HLE; HNE; human leukocyte elastase; leukocyte elastase; Medullasin; NE; Neutrophil elastase; PMN E; PMN elastase; polymorphonuclear elastase; SCN1
Cat. No.: HY-P81215
Synonyms: Bone Marrow Serine Protease; ELA 2; ELA2; ELANE; elastase 2; elastase-2; elastase 2 neutrophil; elastase neutrophil expressed; elastase-2; ELNE_human; GE antibody Granulocyte derived elastase; HLE; HNE; human leukocyte elastase; leukocyte elastase; leukocyte elastase Precursor; Medullasin; NE; Neutrophil elastase; Neutrophill elastase; PMN E; PMN elastase; polymorphonuclear elastase; SCN1; Serine protease; SERP1.
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
