Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
hyperosmotic
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "hyperosmotic" in MCE Product Catalog:
1
1 Cited Publications
Synonyms: D-Isosorbide; Dianhydro-D-glucitol
Target:
Research Areas:
Isosorbide (D-Isosorbide), an orally active vasodilating agent that can be used for the research of heart failure and angina (chest pain). Isosorbide is also an oral hyperosmotic diuretic .
Cat. No.: HY-W716688
Synonyms: D-Isosorbide (Standard); Dianhydro-D-glucitol (Standard)
Research Areas:
Isosorbide (Standard) is the analytical standard of Isosorbide. This product is intended for research and analytical applications. Isosorbide (D-Isosorbide), an orally active vasodilating agent that can be used for the research of heart failure and angina (chest pain). Isosorbide is also an oral hyperosmotic diuretic .
Cat. No.: HY-FL0012
Target:
Research Areas:
Glycerol fructose solution is a hyperosmotic dehydrating agent to lower intracranial pressure and alleviate brain edema. Glycerol and fructose, increase the plasma osmotic pressure, transferring the excess water in the brain tissue to the blood vessels and eliminating it through the kidneys, and sodium chloride can prevent electrolyte imbalance during dehydration.
Cat. No.: HY-180939
Target:
Research Areas:
LFA-1-IN-2 (Compound 25) is a potent LFA-1 inhibitor with a Kd of 21.46 μM. LFA-1-IN-2 inhibits ICAM-1-mediated cell adhesion. LFA-1-IN-2 protects cells from inflammatory hyperosmotic stress. LFA-1-IN-2 improves dry eye disease .
Cat. No.: HY-D3091
CAS No.: 2757681-99-3
Target:
Research Areas:
NRLyso is a lysosome-targeted solvatochromic fluorescent probe derived from Nile Red (HY-D0718). It can localize to lysosomes and is applicable for imaging lysosomal lipid order and polarity. The excitation wavelength of NRLyso is 520 nm, and its emission maximum varies with the environment. NRLyso partitions well into lipid membranes: it exhibits fluorescence enhancement and emission blue-shift in low-polarity, tightly packed lipid environments, while shows emission red-shift in more polar, disordered lipid environments. NRLyso maintains organelle specificity under oxidative and hyperosmotic stress conditions, and can detect changes in lysosomal lipid order and polarity in response to these stresses, cholesterol extraction, and cholesterol enrichment .
Cat. No.: HY-D3092
CAS No.: 2757682-01-0
Target:
Research Areas:
NRERf is an endoplasmic reticulum (ER)-targeted solvatochromic fluorescent probe based on Nile Red (HY-D0718). It possesses ER-targeting capability and can sense changes in local polarity and lipid order of biological membranes. NRERf undergoes excited-state charge transfer, with its emission color changing according to local polarity: the tightly packed, low-polarity liquid-ordered phase (Lo) induces a blue-shifted emission, while the high-polarity liquid-disordered phase (Ld) induces a red-shifted emission. The emission wavelength of NRERf varies with the environment. NRERf can be used to detect changes in lipid order and polarity induced in the ER by cholesterol extraction/enrichment, oxidative stress, and hyperosmotic shock .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
