68 Results for "

interleukin-2 receptor

" in MedChemExpress (MCE) Product Catalog:
Products (68)

68 Results for "interleukin-2 receptor" in MCE Product Catalog:

14
14 Cited Publications
Cat. No.: HY-B0199A
CAS No.: 116680-01-4
Synonyms: RS 61443 hydrochloride; TM-MMF hydrochloride
Mycophenolate mofetil (RS 61443; TM-MMF) hydrochloride is an orally active antimetabolic immunosuppressant with antiproliferative and anti-inflammatory properties. Mycophenolate mofetil hydrochloride significantly inhibits the production of B, T lymphocytes and the proliferation of smooth muscle cells by selectively blocking the de novo purine synthesis pathway. Mycophenolate mofetil hydrochloride effectively reduces adventitial inflammation, medial necrosis and intimal thickening in rat aortic allografts, and decreases the number of lymphocytes expressing the IL-2 receptor, thereby delaying xenograft rejection. Mycophenolate mofetil hydrochloride shows certain toxicity in a hamster-to-rat limb xenotransplantation model when used in combination with FK506 (HY-13756). Mycophenolate mofetil hydrochloride is widely used in studies related to allograft arteriosclerosis (chronic rejection) .
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Cat. No.: HY-108852
CAS No.: 179045-86-4
Purity:  99.73%
Synonyms: CHI 621
Basiliximab (CHI 621) is a recombinant chimeric murine/human IgG1 monoclonal anti-interleukin-2 receptor antibody. Basiliximab can be used for the research of renal transplantation .
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Cat. No.: HY-108738
CAS No.: 152923-56-3
Purity:  99.18%
Synonyms: Ro 24-7375
Daclizumab (Ro 24-7375) is a humanized, monoclonal antibody that blocks CD25 (α-subunit of the high-affinity interleukin-2 receptor (IL-2R-HA)). Daclizumab inhibits effector T cell activation, regulatory T cell (Treg) expansion and survival, and activation-induced T-cell apoptosis. Daclizumab increases IL-2 bioavailability to bind to the intermediate-affinity IL-2R (IL-2R-IA), driving the expansion of anti-inflammatory CD56bright natural killer (NK) cells. Daclizumab can be used for multiple sclerosis and cancer research .
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Cat. No.: HY-P99728
CAS No.: 2056881-92-4
Synonyms: RG7835; RO7049665
Melredableukin alfa (RG7835) is a bivalent conjugate composed of a human IL-2 mutant (T3A, N88D, C125A) and human IgG1. Melredableukin alfa exhibits enhanced Treg cell selectivity in cynomolgus monkey and humanized mouse models. Melredableukin alfa can be used in research related to ulcerative colitis and autoimmune hepatitis .
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Cat. No.: HY-P990086
CAS No.: 2733581-99-0
Synonyms: RG-6292; RO-7296682

Target:  

Interleukin Related

Research Areas:  

Cancer

Vopikitug is an IgG1-kappa, anti-IL2RA (interleukin 2 receptor alpha subunit, IL-2RA, TAC, p55, CD25) homo sapiens monoclonal antibody. Vopikitug shows antineoplastic activity .
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Cat. No.: HY-149056
CAS No.: 2415374-98-8
Purity:  99.94%
Research Areas:  

Cancer

GNE-6893 is an orally active, selective HPK1 inhibitor with a Ki < 0.02 nM. GNE-6893 enhances T cell receptor signaling in primary human T cells. GNE-6893 increases IL2 production in stimulated primary human T cells. GNE-6893 can be used for the research of chronic refractory cancers .
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Cat. No.: HY-135525
CAS No.: 548-42-5
Agroclavine acts as an agonist of the D1-dopamine receptor and α1-adrenergic receptor. Agroclavine enhances the sensitivity of the brain to magnetic fields; it impairs spatial memory without affecting hippocampal long-term potentiation (LTP). Agroclavine exerts bidirectional regulatory effects on immune activity: it enhances NK cell activity with low toxicity under normal conditions, while it inhibits NK cell activity and exhibits significant cardiac and hepatic toxicity under stress conditions. Agroclavine can be used for research on neuroelectrophysiology, learning and memory, and immunoregulation .
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Cat. No.: HY-P991000
CAS No.: 2919583-43-8
Synonyms: AU-007; BD-8; BDG8
Imneskibart (AU-007) is a human monoclonal antibody that binds to the CD25-binding epitope of interleukin-2 (IL-2), blocking the binding of IL-2 to the trimeric IL-2 receptor while retaining the ability to bind to the dimeric IL-2 receptor. Imneskibart expands effector T cell and NK cell populations, reduces regulatory T cells, increases the effector T cell/regulatory T cell ratio, and alleviates vascular leakage. Imneskibart can be used in research related to melanoma and non-small cell lung cancer. The corresponding isotype control is: Human IgG1 kappa, Isotype Control (HY-P99001) .
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Cat. No.: HY-P3736
CAS No.: 137833-31-9
Synonyms: MP-2
Target:  

Interleukin Related

Research Areas:  

Cancer

Myelopeptide-2 is a peptide originally isolated from the supernatant of porcine bone marrow cell cultures, can restore mitogenic reactivity of human T lymphocytes inhibited by HL-60 leukemia cells or measles virus conditions. Myelopeptide-2 also recover depressed interleukin-2 (IL-2) synthesis and interleukin-2 receptor (IL-2R) expression. Myelopeptide-2 involves in immunity homeostasis, is perspective to be applied in antitumor and antivirus research .
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Cat. No.: HY-13232
CAS No.: 1149753-56-9
Target:  

Itk

Research Areas:  

Inflammation/Immunology

ITK antagonist (compound 10 n) is a potent, orally active and selective ITK (Interleukin-2 inducible T-cell kinase) antagonist (IC50=1 and 20 nM in different assays). ITK antagonist inhibits insulin receptor kinase (IRK) with an IC50 of 160 nM .
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Cat. No.: HY-108161
CAS No.: 86187-86-2
Target:  

Interleukin Related

Research Areas:  

Others

LF 1695 is an immunomodulator. LF 1695 enhances the proliferative response of T cells by increasing the production of IL2 (interleukin-2) or the expression of the IL2 receptor. LF 1695 also increases CONA-induced inhibitory activity in human lymphocytes. LF 1695 can be used to study the proliferative and inhibitory activity of T cell subpopulations, as well as their role in immune regulation .
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Cat. No.: HY-W066579
CAS No.: 2305-79-5
4,5,6,7-Tetrahydroindazole acts as an Antimicrobial agent, an interleukin-2-induced T-cell kinase inhibitor, a positive allosteric modulator of AMPA receptors, and a ligand for CYP2E1, with a Kd1 value of 0.023 μM for its binding to rabbit-derived CYP2E1. 4,5,6,7-Tetrahydroindazole scavenges DPPH free radicals. It exhibits anti-tumor, anti-tuberculosis, and anti-inflammatory activities .
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Cat. No.: HY-146671
CAS No.: 2404603-41-2
Target:  

Itk

Research Areas:  

Cancer

ITK inhibitor 5 (compound 27) is a potent and selective ITK inhibitor with IC50s of 5.6, 25 nM for ITK, BTK, respectively .
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Cat. No.: HY-174611
Target:  

mRNA

Research Areas:  

Inflammation/Immunology

Human IL2RA mRNA encodes the human interleukin 2 receptor subunit alpha (IL2RA) protein, a receptor for interleukin-2. IL2RA is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity.
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Cat. No.: HY-145675A
CAS No.: 912342-36-0
Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

(R)-TCB2 is the R-enantiomer of TCB2. TCB2 is a potent anti-human interleukin-2 antibody, facilitates heterodimeric IL-2 receptor signaling and improves anti-tumor immunity .
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Cat. No.: HY-P99664
CAS No.: 152981-31-2

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Inolimomab is an anti-interleukin-2 receptor (IL-2R) α chain monoclonal antibody. Inolimomab improves the survival rate in the early research of treating acute graft-versus-host disease (aGVHD) .
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Cat. No.: HY-P72550
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL2RA; TAC Antigen; Prev. IDDM10; Insulin-Dependent Diabetes Mellitus 10; Prev. IL2R; CD25 Antigen; interleukin-2 receptor Subunit Alpha; IL-2-RA; CD25; IL2-RA; interleukin 2 receptor, Alpha; IMD41; IL-2 receptor Subunit Alpha; TCGFR; IL-2R Subunit Alpha; interleukin 2 receptor Subunit Alpha; P55
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-K2115

MCE HOLO Human Interleukin-2 Receptor (IL-2R) Detection Kit is a homogeneous luminescence-based assay used for the quantitative detection of human IL-2R concentrations in biological samples such as buffer solutions, cell culture supernatants, or serum.

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Cat. No.: HY-P70631
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL2RB; interleukin 2 receptor, Beta; Prev. IL15RB; IL-2R Subunit Beta; High Affinity IL-2 receptor Subunit Beta; CD122 Antigen; interleukin-2 receptor Subunit Beta; IL-2RB; P70-75; P75; CD122; High Affinity IL-2 receptor Beta Subunit; interleukin-15 receptor Subunit Beta; IMD63; interleukin 15 receptor, Beta; interleukin 2 receptor Subunit Beta; IL-2 receptor Subunit Beta
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P70631U
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.; ≥ 95%, as determined by HPLC.
Synonyms: IL2RB; interleukin 2 receptor, Beta; Prev. IL15RB; IL-2R Subunit Beta; High Affinity IL-2 receptor Subunit Beta; CD122 Antigen; interleukin-2 receptor Subunit Beta; IL-2RB; P70-75; P75; CD122; High Affinity IL-2 receptor Beta Subunit; interleukin-15 receptor Subunit Beta; IMD63; interleukin 15 receptor, Beta; interleukin 2 receptor Subunit Beta; IL-2 receptor Subunit Beta
Species:  
Human
Source:  
HEK293
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