4,5,6,7-Tetrahydroindazole
Based on 1 Customer Validation
4,5,6,7-Tetrahydroindazole acts as an Antimicrobial agent, an interleukin-2-induced T-cell kinase inhibitor, a positive allosteric modulator of AMPA receptors, and a ligand for CYP2E1, with a Kd1 value of 0.023 μM for its binding to rabbit-derived CYP2E1. 4,5,6,7-Tetrahydroindazole scavenges DPPH free radicals. It exhibits anti-tumor, anti-tuberculosis, and anti-inflammatory activities.
For research use only. We do not sell to patients.
- CAS No.: 2305-79-5
- Formula: C7H10N2
- Molecular Weight:122.17
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Biological Activity
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IL-2 |
AMPA Receptor |
CYP2E1 |
4,5,6,7-Tetrahydroindazole binds with high affinity to a single site on purified rabbit CYP2E1, with a Kd1 value of 0.023 µM[2].
4,5,6,7-Tetrahydroindazole (0.1-625 µM; 5 min) inhibits 4-nitrophenol oxidation catalyzed by purified rabbit CYP2E1 via a mixed cooperative mechanism, with apparent inhibition constants Kiₐₚ = 1.0 µM and Ksᵢₐₚ = 2.7 µM. It also forms an active ternary complex with a kcat2 of 6.6 min-1[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2305-79-5
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Appearance Solid
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Molecular Weight 122.17
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Formula C7H10N2
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SMILES
N1=CC2=C(N1)CCCC2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
4,5,6,7-Tetrahydroindazole Related Classifications
HY-W066579 Related Classifications
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