7 Results for "

internal modification

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "internal modification" in MCE Product Catalog:

8
8 Cited Publications
Cat. No.: HY-N0086
CAS No.: 1867-73-8
Synonyms: 6-Methyladenosine; N-Methyladenosine
N6-Methyladenosine is the most prevalent internal (non-cap) modification present in the messenger RNA (mRNA) of all higher eukaryotes. N6-Methyladenosine can modifies viral RNAs and has antiviral activities.
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2
2 Cited Publications
Cat. No.: HY-N0086R
CAS No.: 1867-73-8
Synonyms: 6-Methyladenosine (Standard); N-Methyladenosine (Standard)
N6-Methyladenosine (Standard) is the analytical standard of N6-Methyladenosine. This product is intended for research and analytical applications. N6-Methyladenosine is the most prevalent internal (non-cap) modification present in the messenger RNA (mRNA) of all higher eukaryotes. N6-Methyladenosine can modifies viral RNAs and has antiviral activities. In Vitro: N6-methyladenosine (m6A) is selectively recognized by the human YTH domain family 2 (YTHDF2) protein to regulate mRNA degradation. N6-methyladenosine (m6A), a prevalent internal modification in the messenger RNA of all eukaryotes, is post-transcriptionally installed by m6A methyltransferase (e.g., MT-A70) within the consensus sequence of G(m6A)C (70%) or A(m6A)C (30%). N6-methyladenosine (m6A)-containing RNAs are greatly enriched in the YTHDF-bound portion and diminished in the flow-through portion . N6-methyladenosine (m6A), the most abundant internal RNA modification, functions in diverse biological processes, including regulation of embryonic stem cell self-renewal and differentiation. N6-methyladenosine (m6A) is a large protein complex, consisting in part of methyltransferase-like 3 (METTL3) and methyltransferase-like 14 (METTL14) catalytic subunits .
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Cat. No.: HY-N0086S
CAS No.: 139896-43-8
Synonyms: 6-Methyladenosine-d3; N-Methyladenosine-d3
N6-Methyladenosine-d3 (6-Methyladenosine-d3; N-Methyladenosine-d3) is a deuterium labeled N6-Methyladenosine (HY-N0086). N6-Methyladenosine is the most prevalent internal (non-cap) modification present in the messenger RNA (mRNA) of all higher eukaryotes. N6-Methyladenosine can modifies viral RNAs and has antiviral activities.
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Cat. No.: HY-W587663
CAS No.: 21253-58-7
Research Areas:  

Infection

4 '-DTMP is a DHFR inhibitor with Ki of 5.1 nM (DHFR WT) and 34.3 nM (DHFR L28R), respectively. 4 '-DTMP carries a polar modification that induces additional local interactions with the enzyme. In particular, the hairpin structure on the M20 ring is related to the internal communication of the DHFR. 4 '-DTMP has potential inhibition of E.coli .
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Cat. No.: HY-N0086S2
Synonyms: 6-Methyladenosine-13C4; N-Methyladenosine-13C4
N6-Methyladenosine- 13C4 (6-Methyladenosine- 13C4; N-Methyladenosine- 13C4) is 13C-labeled N6-Methyladenosine (HY-N0086). N6-Methyladenosine is the most prevalent internal (non-cap) modification present in the messenger RNA (mRNA) of all higher eukaryotes. N6-Methyladenosine can modifies viral RNAs and has antiviral activities.
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Cat. No.: HY-N0086S3
Synonyms: 6-Methyladenosine-13C3; N-Methyladenosine-13C3
N6-Methyladenosine- 13C3 (6-Methyladenosine- 13C3) is 13C-labeled N6-Methyladenosine (HY-N0086). N6-Methyladenosine is the most prevalent internal (non-cap) modification present in the messenger RNA (mRNA) of all higher eukaryotes. N6-Methyladenosine can modifies viral RNAs and has antiviral activities .
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Cat. No.: HY-185910
Research Areas:  

Others

Palmitamido-C7 CE-Phosphoramidite is a long-chain esterified phosphoramidite monomer used for solid-phase oligonucleotide synthesis. Palmitamido-C7 CE-Phosphoramidite is formed by linking palmitamido to the active end of 2-cyanoethyl phosphoramidite via a C7 alkyl spacer arm. Palmitamido-C7 CE-Phosphoramidite can be used as a building block for nucleic acid chemical modification to synthesize ester-coupled oligonucleotides.
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