3 Results for "

macrophagy

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "macrophagy" in MCE Product Catalog:

Cat. No.: HY-W107409
CAS No.: 213473-00-8
Meridianin C is a marine natural product with anticancer activity. Meridianin C has significant inhibitory effects on four different human tongue cancer cells (YD-8, YD-10B, YD-38 and HSC-3). Meridianin C most strongly reduced the growth of YD-10B cells, the most aggressive and tumorigenic of the cell lines tested. Meridianin C also induced significant accumulation of large vesicles in YD-10B cells, validating its function through macrophagocytosis. Meridianin C reduces cellular levels of Dickkopf-related protein-3 (DKK-3), a known negative regulator of macrophagy. Meridianin C affects macrophagocytosis by downregulating DKK-3, thereby affecting cell proliferation .
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Cat. No.: HY-106282
CAS No.: 917909-71-8
Purity:  98.87%
Target:  

HIV

Research Areas:  

Infection

BIT-225 is an inhibitor for Vpu protein through block of Vpu ion channel, and thus inhibits the release of HIV-1, especially in monocyte-derived macrophages (EC50 is 2.25 μM), without significant cytotoxicity (TC50 is 284 μM) .
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Cat. No.: HY-106282R
CAS No.: 917909-71-8
Target:  

Reference Standards HIV

Research Areas:  

Infection

BIT-225 (Standard) is the analytical standard of BIT-225 (HY-106282). This product is intended for research and analytical applications. BIT-225 is an inhibitor for Vpu protein through block of Vpu ion channel, and thus inhibits the release of HIV-1, especially in monocyte-derived macrophages (EC50 is 2.25 μM), without significant cytotoxicity (TC50 is 284 μM) .
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