19 Results for "

neoplasias

" in MedChemExpress (MCE) Product Catalog:
Products (19)

19 Results for "neoplasias" in MCE Product Catalog:

83
83 Publications Verification
Cat. No.: HY-116215
CAS No.: 186689-07-6
Purity:  99.74%
Target:  

Fluorescent Dye

Research Areas:  

Others

2-NBDG is a fluorescently-labeled deoxyglucose analog that is used primarily to directly monitor glucose uptake by living cells and tissues. It is also used as a topical contrast reagent for the detection of neoplasia. 2-NBDG can be used in real-time confocal, high-resolution, or wide-field fluorescence microscopy as well as in flow cytometry. The probe can be excited by the Argon laser at 488 nm to give the environment-sensitive fluorescence. It has lower photostability than the rhodamine-based fluorescent probes.
loading...
    loading...
62
62 Cited Publications
Cat. No.: HY-B0180
CAS No.: 99011-02-6
Synonyms: R 837
Imiquimod (R 837), an immune response modifier, is a selective toll like receptor 7 (TLR7) agonist. Imiquimod exhibits antiviral and antitumor effects in vivo. Imiquimod can be used for the research of external genital, perianal warts, cancer and COVID-19 .
loading...
    loading...
62
62 Cited Publications
Cat. No.: HY-B0180A
CAS No.: 99011-78-6
Synonyms: R 837 hydrochloride
Imiquimod hydrochloride (R 837 hydrochloride), an immune response modifier, is a selective toll like receptor 7 (TLR7) agonist. Imiquimod hydrochloride exhibits antiviral and antitumor effects in vivo. Imiquimod hydrochloride can be used for the research of external genital, perianal warts, cancer and COVID-19 .
loading...
    loading...
62
62 Cited Publications
Cat. No.: HY-B0180B
CAS No.: 896106-16-4
Imiquimod maleate (R 837 maleate), an immune response modifier, is a selective toll like receptor 7 (TLR7) agonist. Imiquimod maleate exhibits antiviral and antitumor effects in vivo. Imiquimod maleate can be used for the research of external genital, perianal warts, cancer and COVID-19 .
loading...
    loading...
Cat. No.: HY-DY1019
CAS No.: 186689-07-6
2-NBDG (solution) is a fluorescently-labeled deoxyglucose analog that is used primarily to directly monitor glucose uptake by living cells and tissues. It is also used as a topical contrast reagent for the detection of neoplasia. 2-NBDG can be used in real-time confocal, high-resolution, or wide-field fluorescence microscopy as well as in flow cytometry. The probe can be excited by the Argon laser at 488 nm to give the environment-sensitive fluorescence. It has lower photostability than the rhodamine-based fluorescent probes.
Solvent and Concentration: Sterile PBS: 5 mM
loading...
    loading...
Cat. No.: HY-W009776
CAS No.: 38937-66-5
Synonyms: Suberohydroxamic acid; SBHA
Target:  

HDAC Apoptosis

Research Areas:  

Cancer

Suberoyl bis-hydroxamic acid (Suberohydroxamic acid; SBHA) is a competitive and cell-permeable HDAC1 and HDAC3 inhibitor with ID50 values of 0.25 μM and 0.30 μM, respectively .Suberoyl bis-hydroxamic acid renders MM cells susceptible to apoptosis and facilitates the mitochondrial apoptotic pathways .Suberoyl bis-hydroxamic acid can be used for the study of medullary thyroid carcinoma (MTC) .
loading...
    loading...
Cat. No.: HY-151595
CAS No.: 2851841-61-5
Purity:  99.85%
Research Areas:  

Cancer

Menin-MLL inhibitor-22 (compound C20) is an orally active inhibitor of the interaction between menin and mixed lineage leukemia (MLL) (IC50=7 nM). Menin-MLL inhibitor-22 binds menin protein and inhibits cancer cell growth (MV4 cells, IC50=0.3 μM). Menin is a putative tumor suppressor associated with multiple endocrine neoplasia type 1 (MEN-1 syndrome) .
loading...
    loading...
Cat. No.: HY-P1435
CAS No.: 1435893-78-9
Target:  

NADPH Oxidase

Research Areas:  

Cardiovascular Disease Cancer

NoxA1ds is a potent and highly selective NADPH oxidase 1 (NOX1) inhibitor (IC50=20 nM). NoxA1ds inhibits NOX1-derived O 2- production in HT-29 human colon cancer cells. NoxA1ds attenuates VEGF-induced human pulmonary artery endothelial cell migration under hypoxic conditions in vitro. NoxA1ds can be used in the study of hypertension, atherosclerosis and tumors .
loading...
    loading...
Cat. No.: HY-B0180R
CAS No.: 99011-02-6
Synonyms: R 837 (Standard)
Imiquimod (Standard) is the analytical standard of Imiquimod. This product is intended for research and analytical applications. Imiquimod (R 837), an immune response modifier, is a selective toll like receptor 7 (TLR7) agonist. Imiquimod exhibits antiviral and antitumor effects in vivo. Imiquimod can be used for the research of external genital, perianal warts, cancer and COVID-19 .
loading...
    loading...
Cat. No.: HY-B0180AR
CAS No.: 99011-78-6
Synonyms: R 837 hydrochloride (Standard)
Imiquimod (hydrochloride) (Standard) is the analytical standard of Imiquimod (hydrochloride). This product is intended for research and analytical applications. Imiquimod hydrochloride (R 837 hydrochloride), an immune response modifier, is a selective toll like receptor 7 (TLR7) agonist. Imiquimod hydrochloride exhibits antiviral and antitumor effects in vivo. Imiquimod hydrochloride can be used for the research of external genital, perianal warts, cancer and COVID-19 .
loading...
    loading...
Cat. No.: HY-B0180BR
CAS No.: 896106-16-4
Imiquimod (maleate) (Standard) is the analytical standard of Imiquimod (maleate). This product is intended for research and analytical applications. Imiquimod maleate (R 837 maleate), an immune response modifier, is a selective toll like receptor 7 (TLR7) agonist. Imiquimod maleate exhibits antiviral and antitumor effects in vivo. Imiquimod maleate can be used for the research of external genital, perianal warts, cancer and COVID-19 .
loading...
    loading...
Cat. No.: HY-123864
CAS No.: 188804-07-1
Synonyms: S 448
Target:  

Integrin

Research Areas:  

Cardiovascular Disease Cancer

SC-68448 (S 448) is a selective αvβ3 antagonist (IC50 = 1 nM). SC-68448 inhibits αvβ3-mediated endothelial cell proliferation. SC-68448 reduces the total level of αvβ6 in NHBE cells. SC-68448 inhibits angiogenesis in a rat corneal neoplasia model. SC-68448 inhibits tumor growth and completely prevents the development of hypercalcemia in a rat Ledich cell tumor model. SC-68448 can be used in research on cardiovascular and cerebrovascular diseases such as hypercalcemia and cancers such as testicular interstitial cell tumors .
loading...
    loading...
Cat. No.: HY-P4085
CAS No.: 945245-90-9
Target:  

Inhibitory Antibodies

Research Areas:  

Cancer

AGR is a peptide. AGR recognizes lymphatic vessels in fully developed prostate tumors but not in the pre-malignant lesions .
loading...
    loading...
Cat. No.: HY-B0180C
CAS No.: 2995277-02-4
Synonyms: R 837 dihydrochloride
Imiquimod (R 837) dihydrochloride, an immune response modifier, is a selective toll like receptor 7 (TLR7) agonist. Imiquimod exhibits antiviral and antitumor effects in vivo. Imiquimod can be used for the research of external genital, perianal warts, cancer and COVID-19 .
loading...
    loading...
Cat. No.: HY-P992086

Target:  

VEGFR

Research Areas:  

Cancer

Anti-Mouse VEGF Antibody (G6-31) is a anti-mouse VEGF antibody. Anti-Mouse VEGF Antibody (G6-31) blocks VEGF-A-mediated angiogenesis and shows antitumor activity. Anti-Mouse VEGF Antibody (G6-31) can be used for the research of cancer, such as multiple endocrine neoplasia type 1 .
loading...
    loading...
Cat. No.: HY-165119
CAS No.: 96935-44-3
Synonyms: PE(18:0/20:5); 18:0/20:5-PE
Target:  

Endogenous Metabolite

Research Areas:  

Others

1-Stearoyl-2-eicosapentaenoyl-sn-glycero-3-PE (PE(18:0/20:5)) is a phospholipid identified in plasma lipid profile analysis, with similar lipid level changes in high-grade cervical intraepithelial neoplasia and cervical cancer compared with normal state and low-grade cervical intraepithelial neoplasia, and can be used to monitor cervical cancer progression.
loading...
    loading...
Cat. No.: HY-106414
CAS No.: 66211-92-5
Synonyms: NSC 292652; RP 33921
Target:  

Drug Intermediate

Research Areas:  

Cancer

Detorubicin (NSC 292652; RP 33921) is a semi-synthetic anthracycline anticancer agent and a hydrophobic prodrug of Doxorubicin (HY-15142A). Detorubicin enters cancer cells faster and achieves higher intracellular levels than Doxorubicin. Detorubicin localizes exclusively to lysosomes and the nucleus, with unmetabolized Detorubicin accumulating mainly in lysosomes. Detorubicin can be used in research related to hematologic malignancies and L1210 leukemia .
loading...
    loading...
Cat. No.: HY-P992366

Target:  

Galectin Tim3

Research Areas:  

Cancer

HFB200901 is a galectin LGALS9 inhibitor and immunostimulant that can be used in studies related to pancreatic adenocarcinoma, pancreatic intraepithelial neoplasia, KRAS G12C-mutant colon cancer, and prostate cancer. HFB200901 disrupts the LGALS9/TIM-3 axis, while blocking the internalization and vacuolization of recombinant LGALS9. HFB200901 reduces the proportion of regulatory T cells (Treg) and enhances dendritic cell activation, thereby inducing polyfunctional and memory CD8 + T cell responses. HFB200901 inhibits the progression of pancreatic neoplastic lesions and effectively improves the efficacy of PSMA-based vaccination .
loading...
    loading...
Cat. No.: HY-106414A
CAS No.: 64291-45-8
Synonyms: NSC 292652 hydrochloride; RP 33921 hydrochloride
Detorubicin hydrochloride (NSC 292652 hydrochloride) is a semi-synthetic analog of Daunorubicin (HY-13062A) and a prodrug of Doxorubicin (HY-15142A). Detorubicin hydrochloride hydrolyzes to release Doxorubicin under neutral pH conditions. Detorubicin hydrochloride forms complexes with DNA. Detorubicin hydrochloride exhibits anti-hematologic tumor and metastatic melanoma activities. Detorubicin hydrochloride causes myocardial injury, skin damage, alopecia, and high mortality in golden hamsters. Detorubicin hydrochloride can be used in research related to leukemia, and metastatic melanoma .
loading...
    loading...
  • 1