Imiquimod hydrochloride (Standard)
Imiquimod (hydrochloride) (Standard) is the analytical standard of Imiquimod (hydrochloride). This product is intended for research and analytical applications. Imiquimod hydrochloride (R 837 hydrochloride), an immune response modifier, is a selective toll like receptor 7 (TLR7) agonist. Imiquimod hydrochloride exhibits antiviral and antitumor effects in vivo. Imiquimod hydrochloride can be used for the research of external genital, perianal warts, cancer and COVID-19.
For research use only. We do not sell to patients.
- Purity: 98%
- CAS No.: 99011-78-6
- Formula: C14H17ClN4
- Molecular Weight:276.76
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 99011-78-6
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Molecular Weight 276.76
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Formula C14H17ClN4
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SMILES
NC1=NC2=CC=CC=C2C3=C1N=CN3CC(C)C.Cl
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Synonyms
R 837 hydrochloride (Standard)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Athina Angelopoulou, et al. Imiquimod - A toll like receptor 7 agonist - Is an ideal option for management of COVID 19. Environ Res. 2020 Sep; 188: 109858. [Content Brief]
[2]. Yuji Kan, et al. Imiquimod suppresses propagation of herpes simplex virus 1 by upregulation of cystatin A via the adenosine receptor A1 pathway. J Virol. 2012 Oct;86(19):10338-46. [Content Brief]
[3]. Aditya K Gupta, et al. Imiquimod: a review. J Cutan Med Surg. Nov-Dec 2002;6(6):554-60. [Content Brief]
[4]. Michael P Schön, et al. The small antitumoral immune response modifier imiquimod interacts with adenosine receptor signaling in a TLR7- and TLR8-independent fashion. J Invest Dermatol. 2006 Jun;126(6):1338-47. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
- Imiquimod hydrochloride (Standard)
- 99011-78-6
- R 837 hydrochloride (Standard)
- Toll-like Receptor (TLR)
- Autophagy
- SARS-CoV
- HSV
- Reference Standards
- human
- papillomavirus
- warts
- molluscum
- contagiosum
- actinic
- keratosis
- basal ,cell
- carcinoma
- squamous
- cell
- Bowen's
- disease
- nongenital
- infection
- vulvar
- intraepithelial
- neoplasia
- Inhibitor
- inhibitor
- inhibit