1435893-78-9

NoxA1ds Chemical Structure
1435893-78-9

Chemical Structure

NoxA1ds

  • CAS No.: 1435893-78-9
  • Formula:C50H88N14O15
  • Molecular Weight:1125.32

IUPAC Name: (3S,6S,9S,12S,18S,21S,24S)-24-((S)-2-((S)-1-(L-glutamyl)pyrrolidine-2-carboxamido)-3-methylbutanamido)-6,12-bis(4-aminobutyl)-3-carbamoyl-18-isobutyl-2,9,21-trimethyl-5,8,11,14,17,20,23-heptaoxo-4,7,10,13,16,19,22-heptaazahexacosan-26-oic acid

InChIKey: DHBOJLLJKHKZGT-XTGVMIFDSA-N

SMILES: CC(C)[C@@H](C(N)=O)NC([C@H](CCCCN)NC([C@H](C)NC([C@H](CCCCN)NC(CNC([C@H](CC(C)C)NC([C@H](C)NC([C@H](CC(O)=O)NC([C@H](C(C)C)NC([C@H]1N(CCC1)C([C@@H](N)CCC(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

Biological Activity: NoxA1ds is a potent and highly selective NADPH oxidase 1 (NOX1) inhibitor (IC50=20 nM). NoxA1ds inhibits NOX1-derived O2- production in HT-29 human colon cancer cells. NoxA1ds attenuates VEGF-induced human pulmonary artery endothelial cell migration under hypoxic conditions in vitro. NoxA1ds can be used in the study of hypertension, atherosclerosis and tumors[1].

Cat. No. Product Name Purity Description Pricing
HY-P1435 		NoxA1ds 95.34% NoxA1ds is a potent and highly selective NADPH oxidase 1 (NOX1) inhibitor (IC50=20 nM). NoxA1ds inhibits NOX1-derived O2- production in HT-29 human colon cancer cells. NoxA1ds attenuates VEGF-induced human pulmonary artery endothelial cell migration under hypoxic conditions in vitro. NoxA1ds can be used in the study of hypertension, atherosclerosis and tumors.
Pricing 
Expand Hide
loading...
/
  • /
loading...
Size Price
Stock Quantity Availability Operate
/
In-stock
(Estimated to ship on )
(Estimated to ship TODAY)
Estimated to ship on
(Estimated to ship TODAY)

Amount:

USD 0.00

This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

Pricing 
Expand Hide
Structural Analogs

References

Keywords