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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
65 Results for "
neurite growth
" in MedChemExpress (MCE) Product Catalog:
Products (65)
65 Results for "neurite growth" in MCE Product Catalog:
11
11 Publications Verification
Cat. No.: HY-18314
CAS No.: 504433-23-2
Target:
Research Areas:
GW 441756 is a potent and specific nerve growth factor (NGF) receptor tyrosine kinases A (TrkA) inhibitor (IC50=2 nM), which eliminates the BmK NSPK-induced neurite outgrowth .
8
8 Cited Publications
Cat. No.: HY-16594
CAS No.: 133343-34-7
Category:
Target:
7
7 Cited Publications
Target:
Research Areas:
LM11A-31 dihydrochloride, a non-peptide p75 NTR (neurotrophin receptor p75) modulator, is an orally active and potent proNGF (nerve growth factor) antagonist. LM11A-31 dihydrochloride is an amino acid derivative with high blood-brain barrier permeability and blocks p75-mediated cell death. LM11A-31 dihydrochloride reverses cholinergic neurite dystrophy in Alzheimer's disease mouse models with mid- to late-stage disease progression .
7
7 Cited Publications
Target:
Research Areas:
LM11A-31, a non-peptide p75 NTR (neurotrophin receptor p75) modulator, is an orally active and potent proNGF (nerve growth factor) antagonist. LM11A-31 is an amino acid derivative with high blood-brain barrier permeability and blocks p75-mediated cell death. LM11A-31 reverses cholinergic neurite dystrophy in Alzheimer's disease mouse models with mid- to late-stage disease progression .
4
4 Cited Publications
Synonyms: DHEA sulfate; Prasterone sulfate
Category:
Human Gut Microbiota Metabolites Disease markers Endocrine diseases Nervous System Disorder Endogenous metabolite Steroids
Target:
4
4 Cited Publications
Synonyms: DHEA sulfate sodium; Prasterone sulfate sodium
Target:
2
2 Cited Publications
Cat. No.: HY-P4322
CAS No.: 131167-89-0
Research Areas:
2
2 Cited Publications
Cat. No.: HY-P71213
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PTN; HBNF-1; Prev. NEGF1; HBBM; HBNF; Pleiotrophin (Heparin Binding growth Factor 8, neurite growth-Promoting Factor 1); HBGF8; Heparin-Binding neurite Outgrowth Promoting Factor; Heparin-Binding neurite Outgrowth-Promoting Factor 1; Heparin-Binding Neuri
Species:
Mouse
Source:
HEK293
2
2 Cited Publications
Cat. No.: HY-P700138AF
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MDK; Midgestation And Kidney Protein; Prev. NEGF2; ARAP; MK; neurite Outgrowth-Promoting Protein; neurite Outgrowth-Promoting Factor 2; Retinoic Acid Inducible Factor; neurite growth-Promoting Factor 2; Mutant Truncated Midkine B; Amphiregulin-Associated
Species:
Human
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-113416R
CAS No.: 651-48-9
Synonyms: DHEA sulfate (Standard); Prasterone sulfate (Standard)
1
1 Cited Publications
Cat. No.: HY-P73295
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MDK; Midgestation And Kidney Protein; Prev. NEGF2; ARAP; MK; neurite Outgrowth-Promoting Protein; neurite Outgrowth-Promoting Factor 2; Retinoic Acid Inducible Factor; neurite growth-Promoting Factor 2; Mutant Truncated Midkine B; Amphiregulin-Associated
Species:
Human
Source:
Sf9 insect cells
1
1 Cited Publications
Cat. No.: HY-P700223AF
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MDK; Midgestation And Kidney Protein; Prev. NEGF2; ARAP; MK; neurite Outgrowth-Promoting Protein; neurite Outgrowth-Promoting Factor 2; Retinoic Acid Inducible Factor; neurite growth-Promoting Factor 2; Mutant Truncated Midkine B; Amphiregulin-Associated
Species:
Mouse
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P700791
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MDK; Midgestation And Kidney Protein; Prev. NEGF2; ARAP; MK; neurite Outgrowth-Promoting Protein; neurite Outgrowth-Promoting Factor 2; Retinoic Acid Inducible Factor; neurite growth-Promoting Factor 2; Mutant Truncated Midkine B; Amphiregulin-Associated
Species:
Human
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P79419
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MDK; Midgestation And Kidney Protein; Prev. NEGF2; ARAP; MK; neurite Outgrowth-Promoting Protein; neurite Outgrowth-Promoting Factor 2; Retinoic Acid Inducible Factor; neurite growth-Promoting Factor 2; Mutant Truncated Midkine B; Amphiregulin-Associated Protein; MK1; Midkine; FLJ27379
Species:
Mouse
Source:
E. coli
Cat. No.: HY-B0426A
CAS No.: 140462-76-6
Synonyms: ALO4943A; KW4679
Target:
Research Areas:
Infection Neurological Disease Metabolic Disease Inflammation/Immunology
Olopatadine hydrochloride (ALO4943A; KW4679) is an orally active histamine H1 receptor antagonist and mast cell stabilizer. Olopatadine hydrochloride exerts antiallergic effects by blocking histamine H1 receptor-mediated activities. Olopatadine hydrochloride inhibits exocytosis, chemokine release, F-actin polymerization, CXCL10-induced calcium influx, and T cell chemotactic activity. Olopatadine hydrochloride also reduces the expression levels of CXCR3 on the surface of CD4 + and CD8 + T cells. Olopatadine hydrochloride inhibits scratching behavior, improves dermatitis scores, and suppresses intraepidermal neurite outgrowth. Olopatadine hydrochloride simultaneously decreases the levels of inflammatory markers, growth factors, histamine, and specific IgE, while increasing the expression of ErbB3A/HER3A. Olopatadine hydrochloride can be used in research related to seasonal pollinosis, chronic rhinitis, urticaria, allergic conjunctivitis, alopecia areata, and atopic dermatitis .
Research Areas:
PD 174265 is a highly selective, reversible EGFR/ErbB2 tyrosine kinase inhibitor (IC50=0.45 nM) and cell differentiation inducer. By blocking receptor autophosphorylation and the downstream ERK signaling pathway (with an IC50 of 0.45 μM for full-length ERK), PD 174265 effectively inhibits tumor growth and exhibits antitumor activity without obvious toxicity in in vivo models. PD 174265 drives oligodendrocyte precursor cells to switch from a proliferative state to a differentiated state, significantly upregulates the expression of myelin proteins such as CNP, PLP and MBP, and induces neurite branching. PD 174265 shows no inhibitory effect on other kinases including insulin, PDGF and basic FGF receptors, and serves as a crucial tool molecule for investigating the treatment of human epidermoid carcinoma and the mechanism of myelin repair in multiple sclerosis .
Cat. No.: HY-W062109
CAS No.: 113806-05-6
Target:
Research Areas:
Olopatadine (ALO4943A; KW4679) is an orally active histamine H1 receptor antagonist and mast cell stabilizer. Olopatadine exerts antiallergic effects by blocking histamine H1 receptor-mediated activities. Olopatadine inhibits exocytosis, chemokine release, F-actin polymerization, CXCL10-induced calcium influx, and T cell chemotactic activity. Olopatadine also reduces the expression levels of CXCR3 on the surface of CD4 + and CD8 + T cells. Olopatadine inhibits scratching behavior, improves dermatitis scores, and suppresses intraepidermal neurite outgrowth. Olopatadine simultaneously decreases the levels of inflammatory markers, growth factors, histamine, and specific IgE, while increasing the expression of ErbB3A/HER3A. Olopatadine can be used in research related to seasonal pollinosis, chronic rhinitis, urticaria, allergic conjunctivitis, alopecia areata, and atopic dermatitis .
Synonyms: DHEA sulfate sodium-d6; Prasterone sulfate sodium-d6
Cat. No.: HY-116392E
CAS No.: 109836-82-0
Research Areas:
D-threo-PDMP is a potent glucoceramide synthase (GCS) inhibitor, which reduces the glycosphingolipids (such as GM3 and GD3) on the cell surface by inhibiting glycosylation, reduces the total length of the axon plexus and the number of axon branch points, and inhibits neurite growth. D-threo-PDMP inhibits the synthesis of GM3, thereby reducing the adhesion ability of B16 melanoma cells and mimicking the pathological effects of hyperglycemia/TGF-β1. D-threo-PDMP inhibits the synthesis of GD3, thereby protecting liver cells from apoptosis induced by TNF-α. D-threo-PDMP can be used to study diseases related to targeted glycosphingolipid metabolism .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
