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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
19 Results for "
neutral endopeptidase-24.11
" in MedChemExpress (MCE) Product Catalog:
Products (19)
19 Results for "neutral endopeptidase-24.11" in MCE Product Catalog:
Cat. No.: HY-117702
CAS No.: 135949-60-9
Target:
Prolyl Endopeptidase (PREP) Aminopeptidase Opioid Receptor Dopamine Receptor Drug Intermediate
Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology
RB 101 is a blood-brain barrier-crossing prodrug as well as aminopeptidase N and neutral endopeptidase-24.11 inhibitor. RB 101 blocks enkephalin breakdown, elevates extracellular enkephalin levels and activate δ-opioid receptor and dopamine D1 receptor. RB 101 can be used for the research of pain, depressive syndromes, and diabetic neuropathy .
Cat. No.: HY-117702A
Target:
Prolyl Endopeptidase (PREP) Aminopeptidase Opioid Receptor Dopamine Receptor Drug Intermediate
Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology
RB 101 hydrochloride is a blood-brain barrier-crossing prodrug as well as aminopeptidase N and neutral endopeptidase-24.11 inhibitor. RB 101 hydrochloride blocks enkephalin breakdown, elevates extracellular enkephalin levels and activate δ-opioid receptor and dopamine D1 receptor. RB 101 hydrochloride can be used for the research of pain, depressive syndromes, and diabetic neuropathy .
Cat. No.: HY-107762
CAS No.: 261619-50-5
Research Areas:
CGS35066 is a potent and selective aminophosphonate inhibitor of endothelin-converting enzyme-1 (ECE-1). CGS 35066 inhibits the activity of human ECE-1 and rat kidney neutral endopeptidase 24.11 (NEP) in vitro with IC50 values of 22 nM and 2.3 μM, respectively .
Cat. No.: HY-105351
CAS No.: 150126-87-7
Target:
Research Areas:
CGS25155 is an orally active neutral endopeptidase 24.11 (NEP 24.11) inhibitor with an IC50 of 3 nM. CGS25155 can slow down the degradation of the cardiac hormone atrial natriuretic peptide (ANP) and exhibits antihypertensive activity in the DOCA-salt induced rat hypertension model. CGS25155 can be used in cardiovascular disease research .
Cat. No.: HY-171461
CAS No.: 147923-04-4
Target:
Research Areas:
CGS 24592 is an orally active, selective and potent neutral endopeptidase 24.11 (NEP) inhibitor with an IC50 value of 1.6 nmol/L. CGS 24592 reduces the degradation of atrial natriuretic peptide (ANP), increases the concentration of ANP in the plasma, and reduces blood pressure. CGS 24592 is promising for research of cardiovascular disease, such as hypertension and congestive heart failure .
Cat. No.: HY-18211
CAS No.: 849066-09-7
Research Areas:
CGS 35601 is the inhibitor for endothelin-converting enzyme-1 (ECE-1), neutral endopeptidase 24.11 (NEP), and angiotensin-converting enzyme (ACE), with IC50s of 55, 2, and 22 nM, respectively. CGS 35601 suppresses the big endothelin-1 (big ET-1)- and angiotensin I-induced pressor response, and enhances circulation of atrial natriuretic peptide (ANP), regulates the cardiovascular function in SD rats .
Cat. No.: HY-P86377
Synonyms: MME; EPN; Neprilysin; Atriopeptidase; Common acute lymphocytic leukemia antigen; CALLA; Enkephalinase; neutral endopeptidase 24.11; NEP; neutral endopeptidase; Skin fibroblast elastase; SFE; CD10
Cat. No.: HY-P85080
Synonyms: MME; EPN; Neprilysin; Atriopeptidase; Common acute lymphocytic leukemia antigen; CALLA; Enkephalinase; neutral endopeptidase 24.11; NEP; neutral endopeptidase; Skin fibroblast elastase; SFE; CD antigen CD10
Cat. No.: HY-P703804
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: MME; Neprilysin-390; Membrane Metalloendopeptidase; Neprilysin-411; Neprilysin; SFE; CALLA; Membrane Metallo-endopeptidase (neutral endopeptidase, Enkephalinase, CALLA, CD10); NEP; Membrane Metallo-endopeptidase Variant 2; neutral endopeptidase 24.11; Alt
Species:
Cynomolgus
Source:
HEK293
Cat. No.: HY-P72876
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MME; Neprilysin-390; Membrane Metalloendopeptidase; Neprilysin-411; Neprilysin; SFE; CALLA; Membrane Metallo-endopeptidase (neutral endopeptidase, Enkephalinase, CALLA, CD10); NEP; Membrane Metallo-endopeptidase Variant 2; neutral endopeptidase 24.11; Alt
Species:
Human
Source:
HEK293
Cat. No.: HY-P72877
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MME; Neprilysin-390; Membrane Metalloendopeptidase; Neprilysin-411; Neprilysin; SFE; CALLA; Membrane Metallo-endopeptidase (neutral endopeptidase, Enkephalinase, CALLA, CD10); NEP; Membrane Metallo-endopeptidase Variant 2; neutral endopeptidase 24.11; Alt
Species:
Human
Source:
HEK293
Cat. No.: HY-P72878
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: MME; Neprilysin-390; Membrane Metalloendopeptidase; Neprilysin-411; Neprilysin; SFE; CALLA; Membrane Metallo-endopeptidase (neutral endopeptidase, Enkephalinase, CALLA, CD10); NEP; Membrane Metallo-endopeptidase Variant 2; neutral endopeptidase 24.11; Alt
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P73746
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MME; Neprilysin-390; Membrane Metalloendopeptidase; Neprilysin-411; Neprilysin; SFE; CALLA; Membrane Metallo-endopeptidase (neutral endopeptidase, Enkephalinase, CALLA, CD10); NEP; Membrane Metallo-endopeptidase Variant 2; neutral endopeptidase 24.11; Alt
Species:
Rat
Source:
HEK293
Cat. No.: HY-P72876A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MME; Neprilysin-390; Membrane Metalloendopeptidase; Neprilysin-411; Neprilysin; SFE; CALLA; Membrane Metallo-endopeptidase (neutral endopeptidase, Enkephalinase, CALLA, CD10); NEP; Membrane Metallo-endopeptidase Variant 2; neutral endopeptidase 24.11; Alt
Species:
Human
Source:
HEK293
Cat. No.: HY-P75607
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MME; Neprilysin-390; Membrane Metalloendopeptidase; Neprilysin-411; Neprilysin; SFE; CALLA; Membrane Metallo-endopeptidase (neutral endopeptidase, Enkephalinase, CALLA, CD10); NEP; Membrane Metallo-endopeptidase Variant 2; neutral endopeptidase 24.11; Alt
Species:
Rhesus Macaque
Source:
HEK293
Cat. No.: HY-P72505A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MME; Neprilysin-390; Membrane Metalloendopeptidase; Neprilysin-411; Neprilysin; SFE; CALLA; Membrane Metallo-endopeptidase (neutral endopeptidase, Enkephalinase, CALLA, CD10); NEP; Membrane Metallo-endopeptidase Variant 2; neutral endopeptidase 24.11; Alternative Protein MME; Skin Fibroblast Elastase; CD10 Antigen; Atriopeptidase; MME Protein; Enkephalinase; CMT2T; CD10; SCA43; Common Acute Lymphocytic Leukemia Antigen; EPN; neutral endopeptidase
Species:
Human
Source:
HEK293
Cat. No.: HY-P71757
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MME; Neprilysin-390; Membrane Metalloendopeptidase; Neprilysin-411; Neprilysin; SFE; CALLA; Membrane Metallo-endopeptidase (neutral endopeptidase, Enkephalinase, CALLA, CD10); NEP; Membrane Metallo-endopeptidase Variant 2; neutral endopeptidase 24.11; Alt
Species:
Human
Source:
P. pastoris
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
