147923-04-4
Chemical Structure
CGS 24592
- CAS No.: 147923-04-4
- Formula:C19H23N2O6P
- Molecular Weight:406.37
InChIKey: MVRLTBIHUWUGAR-KRWDZBQOSA-N
SMILES: OC(CCNC([C@@H](NCP(O)(O)=O)CC1=CC=C(C2=CC=CC=C2)C=C1)=O)=O
Biological Activity: CGS 24592 is an orally active, selective and potent neutral endopeptidase 24.11 (NEP) inhibitor with an IC50 value of 1.6 nmol/L. CGS 24592 reduces the degradation of atrial natriuretic peptide (ANP), increases the concentration of ANP in the plasma, and reduces blood pressure. CGS 24592 is promising for research of cardiovascular disease, such as hypertension and congestive heart failure[1].
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CGS 24592 | CGS 24592 is an orally active, selective and potent neutral endopeptidase 24.11 (NEP) inhibitor with an IC50 value of 1.6 nmol/L. CGS 24592 reduces the degradation of atrial natriuretic peptide (ANP), increases the concentration of ANP in the plasma, and reduces blood pressure. CGS 24592 is promising for research of cardiovascular disease, such as hypertension and congestive heart failure. | |||||||||||||||||||||
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Keywords
