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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
nuclear envelope
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "nuclear envelope" in MCE Product Catalog:
Synonyms: ITK7
PARP11 inhibitor ITK7 (ITK7) is a potent and selective PARP11 inhibitor. PARP11 inhibitor ITK7 can potently inhibit PARP11 with an IC50 value of 14 nM. PARP11 inhibitor ITK7 can be used for the research of cellular localization .
Cat. No.: HY-E70653
CDK1 is a cyclin-dependent kinase that functions as a serine/threonine protein kinase, and is a key player in cell cycle regulation. CDK1/CycB1 Recombinant Human Active Protein Kinase is an ortholog of CDK1. CDK1/cyclin B1 complexes initiates mitotic entry by phosphorylating a multitude of proteins to condense chromosomes, disrupt the nuclear envelope, and enable microtubules polymerization to attach and to segregate the chromosomes .
Cat. No.: HY-159150
CAS No.: 2762922-66-5
HIV-1 inhibitor-71 (compound 2a) blocks the transport of endocytosed HIV-1 particles into nuclear envelope invagination (NEIs) that can inhibit productive infection .
Cat. No.: HY-184293
PROTAC ATR degrader-4 is a PROTAC-based ATR kinase degrader, with a DC50 of 6.18 μM and a Dmax of 71.42% in LoVo cells. PROTAC ATR degrader-4 downregulates ATR protein expression, inducing nuclear envelope rupture, genomic instability, DNA damage and apoptosis. PROTAC ATR degrader-4 exhibits anti-tumor activity in xenograft tumor mouse models and can be used for the research of atm-deficient cancers .
Cat. No.: HY-P810459
Synonyms: SYNE3, Spectrin Repeat Containing nuclear envelope Family Member 3, Nesprin-3, LINC00341, NET53, Long Intergenic Non-Protein Coding RNA 341, nuclear envelope Spectrin Repeat Protein 3, KASH Domain-Containing Protein 3, NCRNA00341, C14orf139, FLJ25605, C14orf49, Nesp3, KASH3, Chromosome 14 Open Reading Frame 139, Chromosome 14 Open Reading Frame 49, Uncharacterized Protein C14orf113, Non-Protein Coding RNA 341, C14ORF139, NESPRIN-3, C14ORF49, NESP3
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
