nutraceutical

By Targets:	Apoptosis (2) Biochemical Assay Reagents (2) Drug Derivative (1) Endogenous Metabolite (2)
By Research Areas:	Cancer (3) Cardiovascular Disease (1) Inflammation/Immunology (6) Metabolic Disease (2)
Oligonucleotides:	Cholesterol (1)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0171

Beta-Sitosterol (purity>80%) 20+ Cited Publications	Apoptosis Endogenous Metabolite	Cardiovascular Disease Inflammation/Immunology Cancer
Beta-Sitosterol (purity≥80%) is orally active. Beta-Sitosterol exhibits multiple activities, including anti-inflammatory, anticancer, antioxidant, antimicrobial, antidiabetic, antioxidant enzyme, and analgesic. Beta-Sitosterol inhibits inflammation and impaired adipogenesis in bovine mammary epithelial cells by reducing levels of ROS, TNF-α, IL-1β, and NF-κB p65 and restoring the activity of the HIF-1α/mTOR signaling pathway. Beta-Sitosterol induces apoptosis in cancer cells through ROS-mediated mitochondrial dysregulation and p53 activation. Beta-Sitosterol exerts its anticancer effects in cancer cells by activating caspase-3, caspase-8, and caspase-9, mediating PARP inactivation, MMP loss, altered Bcl-2-Bax ratio, and cytochrome c release. Beta-Sitosterol modulates macrophage polarization and reduces rheumatoid inflammation in mice. Beta-Sitosterol inhibits tumor growth in multiple mouse cancer models. Beta-Sitosterol can be used in the research of arthritis, lung cancer, breast cancer and other cancers, diabetes, etc .

HY-N7072

Grape seed extract 2 Publications Verification	Apoptosis	Metabolic Disease Inflammation/Immunology Cancer
Grape seed extract is a natural product, with anti-inflammatory and anti-proliferative effects. Grape seed extract shows inhibitory activity on the fat-metabolizing enzymes pancreatic lipase and lipoprotein lipase. Grape seed extract induces apoptotic in human colorectal cancer cells .

HY-N10514

Lacto-N-triose II	Others	Others
Lacto-N-triose II is a core structural unit of human milk oligosaccharides (HMOs). Lacto-N-triose II owns nutraceutical potentials and can be used in the production of complex HMOs .

HY-120987

Ethyl stearidonate	Biochemical Assay Reagents	Others
6,9,12,15-octadecatetraenoic acid (Glycerol α-monoelaidate) is a rare omega-3 series polyunsaturated fatty acid. In normal people, it accounts for less than 0.25% of serum phospholipid fatty acids. It is found in certain natural oils, such as echium and blackcurrant, and to the extent that these oils are incorporated into nutraceuticals, stearidonic acid can be an important polyunsaturated species in the human diet. Ethyl stearidonic acid, an ester of the free acid, is less water soluble but more suitable for formulating stearidonic acid-containing diets and dietary supplements.

HY-N12777

Coixenolide	Endogenous Metabolite	Metabolic Disease Inflammation/Immunology Cancer
Coixenolide can be isolated from coix seeds, and exhibits anti-inflammatory, anti-tumor and pain-reducing activities. Coixenolide stimulates the lung, heart, striated and smooth muscles at low doses, while inhibits at high doses. Coixenolide dilates pulmonary veins and improves pulmonary blood circulation. Coixenolide can also be used as nutraceuticals and functional foods. Coixenolide enhances the prodcutionof mycelia biomass and polysaccharides when added to the media of submerged culture of G. lucidum. Coixenolide affects the synthesis level of phosphoglucose isomerase and α-phosphoglucomutase .

HY-N10059

Quebecol	Others	Inflammation/Immunology
Quebecol is a nutraceutical agent against periodontitis.

HY-W720042A

(rac)-Zeaxanthin dimethyl ether	Biochemical Assay Reagents	Others
(rac)-Zeaxanthin dimethyl ether is the racemate of Zeaxanthin dimethyl ester. Zeaxanthin is a type of xanthophyll. (rac)-Zeaxanthin dimethyl ether has applications as pharmaceuticals and nutraceuticals and in the food industry .

HY-N12028

Acacetin 7-O-glucuronide	Others	Others
Acacetin 7-O-glucuronide is a glucuronide isolated from the methanolic leaf extract of Acacetin. Acacetin 7-O-glucuronide has potential applications in the development of nutraceuticals and pharmaceutical formulations .

HY-N18749

Raspberry naturome extract	Others	Inflammation/Immunology
Raspberry naturome extract is an extract used in nutraceuticals and food science. Ideal for studying the antioxidant and anti-inflammatory properties of raspberry compounds.

HY-N18243

5-O-(E)-p-Coumaroylquinic acid methyl ester	Drug Derivative	Inflammation/Immunology
O-(E)-p-Coumaroylquinic acid methyl ester is a coumaric acid derivative found in the flowers of Vaccinium corymbosum. O-(E)-p-Coumaroylquinic acid methyl ester shows antioxidant effects and can be used for nutraceutical and functional food applications .

Cat. No.	Product Name

HY-L068

Flavonoids Library	576 compounds
Flavonoids are an important class of natural products; particularly, they belong to a class of plant secondary metabolites having a polyphenolic structure, widely found in fruits, vegetables and certain beverages. Flavonoids can be subdivided into different subgroups depending on the carbon of the C ring on which the B ring is attached and the degree of unsaturation and oxidation of the C ring. These subgroups are: flavones, flavonols, flavanones, flavanonols, flavanols or catechins, anthocyanins and chalcones. Flavonoids are now considered as an indispensable component in a variety of nutraceutical, pharmaceutical, medicinal and cosmetic applications. This is attributed to their anti-oxidative, anti-inflammatory, anti-mutagenic and anti-carcinogenic properties coupled with their capacity to modulate key cellular enzyme function. Naturally occurring flavonoids are known to have biological activities for use as drugs, for example, in diseases like cancer, Alzheimer’s disease (AD), atherosclerosis, etc. MCE offers a unique collection of 576 natural flavonoid compounds which is a useful tool for drug discovery as an important source of lead compounds.

Flavonoids Library

576 compounds

Flavonoids are an important class of natural products; particularly, they belong to a class of plant secondary metabolites having a polyphenolic structure, widely found in fruits, vegetables and certain beverages. Flavonoids can be subdivided into different subgroups depending on the carbon of the C ring on which the B ring is attached and the degree of unsaturation and oxidation of the C ring. These subgroups are: flavones, flavonols, flavanones, flavanonols, flavanols or catechins, anthocyanins and chalcones. Flavonoids are now considered as an indispensable component in a variety of nutraceutical, pharmaceutical, medicinal and cosmetic applications. This is attributed to their anti-oxidative, anti-inflammatory, anti-mutagenic and anti-carcinogenic properties coupled with their capacity to modulate key cellular enzyme function. Naturally occurring flavonoids are known to have biological activities for use as drugs, for example, in diseases like cancer, Alzheimer’s disease (AD), atherosclerosis, etc.

MCE offers a unique collection of 576 natural flavonoid compounds which is a useful tool for drug discovery as an important source of lead compounds.

Cat. No.	Product Name	Type

HY-120987

Ethyl stearidonate	Biochemical Assay Reagents
6,9,12,15-octadecatetraenoic acid (Glycerol α-monoelaidate) is a rare omega-3 series polyunsaturated fatty acid. In normal people, it accounts for less than 0.25% of serum phospholipid fatty acids. It is found in certain natural oils, such as echium and blackcurrant, and to the extent that these oils are incorporated into nutraceuticals, stearidonic acid can be an important polyunsaturated species in the human diet. Ethyl stearidonic acid, an ester of the free acid, is less water soluble but more suitable for formulating stearidonic acid-containing diets and dietary supplements.

Ethyl stearidonate

Biochemical Assay Reagents

6,9,12,15-octadecatetraenoic acid (Glycerol α-monoelaidate) is a rare omega-3 series polyunsaturated fatty acid. In normal people, it accounts for less than 0.25% of serum phospholipid fatty acids. It is found in certain natural oils, such as echium and blackcurrant, and to the extent that these oils are incorporated into nutraceuticals, stearidonic acid can be an important polyunsaturated species in the human diet. Ethyl stearidonic acid, an ester of the free acid, is less water soluble but more suitable for formulating stearidonic acid-containing diets and dietary supplements.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0171

Beta-Sitosterol (purity>80%) 20+ Cited Publications	Cardiovascular Disease other families Classification of Application Fields Leguminosae Plants Endogenous metabolite Glycyrrhiza uralensis Fisch. Inflammation/Immunology Disease Research Fields Steroids Source Classification	Apoptosis Endogenous Metabolite
Beta-Sitosterol (purity≥80%) is orally active. Beta-Sitosterol exhibits multiple activities, including anti-inflammatory, anticancer, antioxidant, antimicrobial, antidiabetic, antioxidant enzyme, and analgesic. Beta-Sitosterol inhibits inflammation and impaired adipogenesis in bovine mammary epithelial cells by reducing levels of ROS, TNF-α, IL-1β, and NF-κB p65 and restoring the activity of the HIF-1α/mTOR signaling pathway. Beta-Sitosterol induces apoptosis in cancer cells through ROS-mediated mitochondrial dysregulation and p53 activation. Beta-Sitosterol exerts its anticancer effects in cancer cells by activating caspase-3, caspase-8, and caspase-9, mediating PARP inactivation, MMP loss, altered Bcl-2-Bax ratio, and cytochrome c release. Beta-Sitosterol modulates macrophage polarization and reduces rheumatoid inflammation in mice. Beta-Sitosterol inhibits tumor growth in multiple mouse cancer models. Beta-Sitosterol can be used in the research of arthritis, lung cancer, breast cancer and other cancers, diabetes, etc .

HY-N7072

Grape seed extract 2 Publications Verification	Natural Products Classification of Application Fields Vitis vinifera cv. Zalema Metabolic Disease Plants Vitaceae Disease Research Fields Inflammation/Immunology Source Classification	Apoptosis
Grape seed extract is a natural product, with anti-inflammatory and anti-proliferative effects. Grape seed extract shows inhibitory activity on the fat-metabolizing enzymes pancreatic lipase and lipoprotein lipase. Grape seed extract induces apoptotic in human colorectal cancer cells .

HY-N10514

Lacto-N-triose II	Polysaccharides Classification of Application Fields Animals Other Diseases Disease Research Fields Saccharides	Others
Lacto-N-triose II is a core structural unit of human milk oligosaccharides (HMOs). Lacto-N-triose II owns nutraceutical potentials and can be used in the production of complex HMOs .

HY-N12777

Coixenolide	Natural Products Gramineae Coix lacryma-jobi Linn. Plants Source Classification	Endogenous Metabolite
Coixenolide can be isolated from coix seeds, and exhibits anti-inflammatory, anti-tumor and pain-reducing activities. Coixenolide stimulates the lung, heart, striated and smooth muscles at low doses, while inhibits at high doses. Coixenolide dilates pulmonary veins and improves pulmonary blood circulation. Coixenolide can also be used as nutraceuticals and functional foods. Coixenolide enhances the prodcutionof mycelia biomass and polysaccharides when added to the media of submerged culture of G. lucidum. Coixenolide affects the synthesis level of phosphoglucose isomerase and α-phosphoglucomutase .

HY-N10059

Quebecol	other families Classification of Application Fields Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology Source Classification	Others
Quebecol is a nutraceutical agent against periodontitis.

HY-W720042A

(rac)-Zeaxanthin dimethyl ether	Natural Products Microorganisms Source Classification	Biochemical Assay Reagents
(rac)-Zeaxanthin dimethyl ether is the racemate of Zeaxanthin dimethyl ester. Zeaxanthin is a type of xanthophyll. (rac)-Zeaxanthin dimethyl ether has applications as pharmaceuticals and nutraceuticals and in the food industry .

HY-N12028

Acacetin 7-O-glucuronide	Flavonoids Flavones Labiatae Plants Vernonia Schreb. Source Classification	Others
Acacetin 7-O-glucuronide is a glucuronide isolated from the methanolic leaf extract of Acacetin. Acacetin 7-O-glucuronide has potential applications in the development of nutraceuticals and pharmaceutical formulations .

HY-N18749

Raspberry naturome extract	Structural Classification Extract	Others
Raspberry naturome extract is an extract used in nutraceuticals and food science. Ideal for studying the antioxidant and anti-inflammatory properties of raspberry compounds.

HY-N18243

5-O-(E)-p-Coumaroylquinic acid methyl ester	Structural Classification Monophenols Vaccinium corymbosum L. Phenols Ericaceae Plants Source Classification	Drug Derivative
O-(E)-p-Coumaroylquinic acid methyl ester is a coumaric acid derivative found in the flowers of Vaccinium corymbosum. O-(E)-p-Coumaroylquinic acid methyl ester shows antioxidant effects and can be used for nutraceutical and functional food applications .

Cat. No.	Product Name		Classification

HY-N0171

Beta-Sitosterol (purity>80%) 20+ Cited Publications		Cholesterol
Beta-Sitosterol (purity≥80%) is orally active. Beta-Sitosterol exhibits multiple activities, including anti-inflammatory, anticancer, antioxidant, antimicrobial, antidiabetic, antioxidant enzyme, and analgesic. Beta-Sitosterol inhibits inflammation and impaired adipogenesis in bovine mammary epithelial cells by reducing levels of ROS, TNF-α, IL-1β, and NF-κB p65 and restoring the activity of the HIF-1α/mTOR signaling pathway. Beta-Sitosterol induces apoptosis in cancer cells through ROS-mediated mitochondrial dysregulation and p53 activation. Beta-Sitosterol exerts its anticancer effects in cancer cells by activating caspase-3, caspase-8, and caspase-9, mediating PARP inactivation, MMP loss, altered Bcl-2-Bax ratio, and cytochrome c release. Beta-Sitosterol modulates macrophage polarization and reduces rheumatoid inflammation in mice. Beta-Sitosterol inhibits tumor growth in multiple mouse cancer models. Beta-Sitosterol can be used in the research of arthritis, lung cancer, breast cancer and other cancers, diabetes, etc .

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nutraceutical

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