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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
orthotopic glioma models
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "orthotopic glioma models" in MCE Product Catalog:
Cat. No.: HY-P11287A
Research Areas:
Cat. No.: HY-P11287
Research Areas:
Cat. No.: HY-173116
CAS No.: 2051527-54-7
Target:
Research Areas:
DOTA-XYIMSR-01 is a molecular probe targeting CAIX that can be labeled with 177Lu for the inhibition and localization of malignant gliomas. The uptake of [177Lu] Lu-XYIMSR-01 in U87MG tumors is 6.19 % of the injected dose per gram (% ID/g), and the tumor-to-muscle uptake ratio is 20.14. In the orthotopic glioma model, combined injection with Temozolomide (HY-17364) can significantly improve the survival rate of mice and inhibit tumor growth. DOTA-XYIMSR-01 shows promise for research in the field of anti-cancer therapy .
Cat. No.: HY-N19738
CAS No.: 21105-15-7
Cat. No.: HY-157828
CAS No.: 2376765-57-8
Target:
Research Areas:
DSP-0390 is an orally active inhibitor of emopamil binding protein (EBP). DSP-0390 induces cell death by blocking cholesterol biosynthesis in tumor cells. DSP-0390 exhibits antitumor activity in an orthotopic xenograft model of human glioblastoma. DSP-0390 can be used for the research of recurrent high-grade gliomas .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
