348 Results for "

oxidoreductase

" in MedChemExpress (MCE) Product Catalog:
Products (348)

348 Results for "oxidoreductase" in MCE Product Catalog:

192
192 Publications Verification
Cat. No.: HY-15924
CAS No.: 298-93-1
Synonyms: MTT; Thiazolyl Blue Tetrazolium bromide; Methylthiazolyldiphenyl-tetrazolium bromide
Thiazolyl Blue (MTT) is a cell-permeable and positively charged tetrazolium dye that is used to detect reductive metabolism in cells. Thiazolyl Blue is taken up by cells through the plasma membrane and then reduced to formazan by intracellular NAD (P) H-oxidoreductases. Thiazolyl Blue is frequently used in colorimetric assays to measure cell proliferation, cytotoxicity, and apoptosis .
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14
14 Cited Publications
Cat. No.: HY-N0645
CAS No.: 66-76-2
Synonyms: Dicumarol
Dicoumarol is an inhibitor of both NAD(P)H:quinone oxidoreductase 1 (NQO1) and PDK1 with IC50s of 0.37 and 19.42 μM, respectively.
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10
10 Cited Publications
Cat. No.: HY-123962
CAS No.: 421581-52-4
Purity:  98.18%
Target:  

NADPH Oxidase

Research Areas:  

Metabolic Disease

G6PD activator AG1 is a potent and selective glucose-6-phosphate dehydrogenase (G6PD) agonist with an EC50 of 3 μM. G6PD is an oxidoreductase that catalyzes the oxidation of glucose-6-phosphate to 6-phosphogluconolactone and the simultaneous reduction of NAD phosphate (NADP) to reduced NADP (NADPH). G6PD activator AG1 can reduce hemolysis of human erythrocytes .
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8
8 Cited Publications
Cat. No.: HY-P2902
CAS No.: 9001-37-0
Research Areas:  

Cancer

Glucose oxidase is used in the food and beverage industry as a preservative and stabilizer and is commonly derived from the fungus Aspergillus niger. Glucose oxidase can react with intracellular glucose and oxygen (O2) to produce hydrogen peroxide (H2O2) and gluconic acid, which can cut off the nutrition source of cancer cells and consequently inhibit their proliferation .
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8
8 Cited Publications
Cat. No.: HY-14874
CAS No.: 577778-58-6
Purity:  99.06%
Synonyms: FYX-051
Research Areas:  

Metabolic Disease

Topiroxostat (FYX-051) is a potent and orally active xanthine oxidoreductase (XOR) inhibitor with an IC50 value of 5.3 nM and a Ki value of 5.7 nM. Topiroxostat exhibits weak CYP3A4-inhibitory activity (18.6%). Topiroxostat has the potential for hyperuricemia treatment .
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6
6 Cited Publications
Cat. No.: HY-P2755
CAS No.: 9002-17-9
Synonyms: XO; XOD
Xanthine oxidase, Microorganism (XO) is a xanthine oxidoreductase enzyme that generates reactive oxygen species (ROS), catalyzes the oxidation of hypoxanthine to xanthine, and further catalyzes the oxidation of xanthine to uric acid .
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5
5 Cited Publications
Cat. No.: HY-114936
CAS No.: 2738-64-9
Purity:  ≥99.0%
Synonyms: AR-054
Piericidin A (AR-054) is a natural mitochondrial NADH-ubiquinone oxidoreductase (complex I) inhibitor. Piericidin A is a potent neurotoxin and inhibits mitochondrial respiration by disrupting the electron transport system through its action on NADH-ubiquinone reductase. Piericidin A is also a potential quorum-sensing inhibitor that suppresses the expression of the virulence genes of Erwinia carotovora subsp. atroseptica (Eca). Piericidin A is an ADC cytotoxin and has anti-bacterial, anticancer, insecticidal activity .
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3
3 Cited Publications
Cat. No.: HY-103667
CAS No.: 131359-24-5
Purity:  99.46%
Research Areas:  

Cancer

2-HBA is a potent inducer of NAD(P)H:quinone acceptor oxidoreductase 1 (NQO1) which can also activate caspase-3 and caspase-10.
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2
2 Cited Publications
Cat. No.: HY-141552
CAS No.: 2452401-65-7
Purity:  99.61%
Research Areas:  

Cardiovascular Disease

FC9402 is a potent and selective sulfide quinone oxidoreductase (SQOR) inhibitor extracted from patent WO 2020/146636 A1. FC9402 attenuates TAC-induced cardiomyocyte hypertrophy and left ventricle (LV) fibrosis. FC9402 can be used for cardiovascular regulation .
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2
2 Cited Publications
Cat. No.: HY-P82344
Synonyms: MT-ND1; MTND1; NADH1; ND1; NADH-ubiquinone oxidoreductase chain 1; NADH dehydrogenase subunit 1

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human, Mouse, Rat

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2
2 Cited Publications
Cat. No.: HY-P80251
Synonyms: DIA4, NMOR1, NQO1, NAD(P)H dehydrogenase [quinone] 1, Azoreductase, DT-diaphorase, Menadione reductase, NAD(P)H:quinone oxidoreductase 1, Phylloquinone reductase, Quinone reductase 1, DTD, QR1

Host:  

Rabbit

Application:  

WB, ICC/IF, IP, FC

Reactivity:  

Human, Mouse

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1
1 Cited Publications
Cat. No.: HY-P74405A
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NQO1; DHQU; Prev. NMOR1; NAD(P)H Dehydrogenase, Quinone 1; Prev. DIA4; NAD(P)H-Quinone oxidoreductase; DT-Diaphorase; NAD(P)H:Quinone Acceptor oxidoreductase Type 1; QR1; NAD(P)H:Menadione oxidoreductase 1; DTD; NAD(P)H:Quinone Oxireductase; NAD(P)H Dehyd
Species:  
Human
Source:  
E. coli
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1
1 Cited Publications
Cat. No.: HY-P2897
CAS No.: 9028-36-8
Synonyms: D-LDH
Target:  

Lactate Dehydrogenase

Research Areas:  

Others

D-Lactate dehydrogenase, Microorganism (D-LDH) is an oxidoreductase that uses NAD + or NADP + as an acceptor and acts on the donor CH-OH group, and can catalyze the oxidation of D-lactate to pyruvate. D-Lactate dehydrogenase widely exists in bacteria and fungi, and is often used in biochemical research .
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1
1 Cited Publications
Cat. No.: HY-128895
CAS No.: 1800405-30-4
Purity:  99.94%
KL1333, a derivative of β-lapachone, is an orally available NAD+ modulator. KL1333 reacts with NAD(P)H:quinone oxidoreductase 1 (NQO1) as a substrate, resulting in increases in intracellular NAD+ levels via NADH oxidation. KL1333 improves energy metabolism and mitochondrial dysfunction in MELAS fibroblasts. KL1333 protects against Cisplatin-induced ototoxicity in mouse cochlear cultures .
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1
1 Cited Publications
Cat. No.: HY-P70893
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ERO1A; Ero1alpha; Prev. ERO1L; ERO1-L-Alpha; Endoplasmic Reticulum oxidoreductase Alpha; ERO1-L; ERO1-Like Protein Alpha; ERO1 (S. Cerevisiae)-Like; Oxidoreductin-1-L-Alpha; ERO1-Like (S. Cerevisiae); ERO1-Alpha; ERO1LA; Endoplasmic Reticulum Oxidoreducta
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P81196
Synonyms: 3BHS1_HUMAN; 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1; beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I; 3-beta-HSD I; 3-beta-hydroxy-5-ene steroid dehydrogenase 1; 3-beta-hydroxy-Delta(5)-steroid dehydrogenase 1; EC:1.1.1.145; 3-beta-hydroxysteroid 3-dehydrogenase 1; EC:1.1.1.270; Delta-5-3-ketosteroid isomerase; Dihydrotestosterone oxidoreductase. EC:1.1.1.210; Steroid Delta-isomerase 1; EC:5.3.3.1; Trophoblast antigen FDO161G; 3BH; HSDB3A;

Host:  

Rabbit

Application:  

WB, ICC/IF

Reactivity:  

Human

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Cat. No.: HY-P2907
CAS No.: 9028-85-7
Research Areas:  

Others

Formate dehydrogenase is a class of oxidoreductases widely distributed in bacteria, fungi, plants and animals. Formate dehydrogenase catalyzes the reversible conversion between formic acid and carbon dioxide, accompanied by redox reactions of the coenzyme NAD +/NADH or other electron carriers .
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Cat. No.: HY-125027
CAS No.: 1430798-22-3
Purity:  99.70%
Synonyms: IB-DNQ
Target:  

Quinone Reductase

Research Areas:  

Cancer

Isobutyl-deoxynyboquinone (IB-DNQ) is a selective substrate for NAD(P)H:quinone oxidoreductase (NQO1). Isobutyl-deoxynyboquinone can be used for the research of anticancer .
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Cat. No.: HY-144439
CAS No.: 118666-03-8
Purity:  99.94%
HTS07545 is a sulfide:quinone oxidoreductase (SQOR) inhibitor with an IC50 of 30 nM. HTS07545 inhibits SQOR function and mediates resistance to ferroptosis. HTS07545 reduces tumor volume and weight of pancreatic ductal adenocarcinoma. HTS07545 induces tumor cell nuclear necrosis. The combination of HTS07545 and Erastin (HY-15763) exerts a synergistic effect without causing significant weight loss in mice. HTS07545 can be used in studies related to pancreatic ductal adenocarcinoma and heart failure [1] [2].
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Cat. No.: HY-P2889
CAS No.: 37250-80-9
Research Areas:  

Others

Pyranose oxidase, Coriolus sp. is an oxidoreductase targeting monosaccharides (e.g., D-glucose, D-galactose). Pyranose oxidase, Coriolus sp. is promising for research of biosensors (glucose, 1,5-anhydroglucitol detection) and biofuel cells .
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