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Results for "

parasite viability

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

2

Natural
Products

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N6950
    Hederacolchiside A1
    1 Publications Verification

    		 PI3K Akt mTOR Parasite Apoptosis Infection Cancer
    Hederacolchiside A1, isolated from Pulsatilla chinensis, suppresses proliferation of tumor cells by inducing apoptosis through modulating PI3K/Akt/mTOR signaling pathway . Hederacolchiside A1 has antischistosomal activity, affecting parasite viability both in vivo and in vitro .
    Hederacolchiside A1
  • HY-151574
    PfGSK3/PfPK6-IN-1

    		Ser/Thr Kinase Parasite GSK-3 Infection
    PfGSK3/PfPK6-IN-1 is a dual Plasmodium serine/threonine kinase inhibitor, with an IC50 of 97 nM against PfGSK3 and 8 nM against PfPK6 of Plasmodium falciparum. PfGSK3/PfPK6-IN-1 inhibits the proliferation of blood-stage parasites of Plasmodium falciparum 3D7. PfGSK3/PfPK6-IN-1 shows low cytotoxicity to hepatocytes at a concentration of 200 nM, and reduces cell viability at a concentration of 2 μM. PfGSK3/PfPK6-IN-1 is applicable to malaria-related research .
    PfGSK3/PfPK6-IN-1
  • HY-185218
    WR 146459

    		Parasite Infection
    WR 146459 is an orally active 9-phenanthrenecarbinol and antimalarial agent. WR 146459 bears a 2-piperidyl substituent on its 9-carbinol moiety. WR 146459 inhibits hypoxanthine uptake by Plasmodium falciparum strains, reducing parasite viability. WR 146459 can be used for the research of malaria .
    WR 146459
  • HY-N6950R
    Hederacolchiside A1 (Standard)

    		Reference Standards PI3K Akt mTOR Parasite Apoptosis Infection Cancer
    Hederacolchiside A1 (Standard) is the analytical standard of Hederacolchiside A1. This product is intended for research and analytical applications. Hederacolchiside A1, isolated from Pulsatilla chinensis, suppresses proliferation of tumor cells by inducing apoptosis through modulating PI3K/Akt/mTOR signaling pathway . Hederacolchiside A1 has antischistosomal activity, affecting parasite viability both in vivo and in vitro .
    Hederacolchiside A1 (Standard)

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