15 Results for "

phenylalanine hydroxylase

" in MedChemExpress (MCE) Product Catalog:
Products (15)

15 Results for "phenylalanine hydroxylase" in MCE Product Catalog:

5
5 Cited Publications
Cat. No.: HY-101456
CAS No.: 14173-40-1
Purity:  99.89%
Synonyms: 4-Chloro-DL-phenylalanine methyl ester hydrochloride
PCPA methyl ester hydrochloride (4-Chloro-DL-phenylalanine methyl ester hydrochloride), a reversible tryptophan hydroxylase inhibitor, is a serotonin (5-HT) synthesis inhibitor. PCPA methyl ester hydrochloride crosses the blood brain barrier and reduces 5-HT central availability .
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3
3 Cited Publications
Cat. No.: HY-A0124A
CAS No.: 69056-38-8
Synonyms: (6R)-BH4 dihydrochloride; (6R)-Tetrahydro-L-biopterin dihydrochloride
Sapropterin ((6R)-BH4; (6R)-Tetrahydro-L-biopterin) dihydrochloride is an orally active phenylalanine hydroxylase (PAH) cofactor, which is effective in reducing blood phenylalanine concentrations. Sapropterin dihydrochloride can be used in study of phenylketonuria (PKU) phenylketonuria. Sapropterin dihydrochloride can aggravate experimental autoimmune encephalomyelitis (EAE) .
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1
1 Cited Publications
Cat. No.: HY-112234
CAS No.: 17094-01-8
Synonyms: Sepiapterin
L-Sepiapterin (Sepiapterin), is a phenylalanine hydroxylase activator, is a precursor of the endothelial nitric oxide synthase (eNOS) cofactor tetrahydrobiopterin (BH4). L-Sepiapterin improves endothelial dysfunction in small mesenteric arteries from db/db mice, and induces angiogenesis. L-Sepiapterin inhibits cell proliferation and migration of ovarian cancer cells via down-regulation of p70 S6K-dependent VEGFR-2 expression. L-Sepiapterin can be used for the study of hyperphenylalaninemia .
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1
1 Cited Publications
Cat. No.: HY-23460
CAS No.: 278605-15-5
Synonyms: 4-Ethynyl-L-phenylalanine
Research Areas:  

Neurological Disease

p-Ethynylphenylalanine (4-Ethynyl-L-phenylalanine) is a potent, selective, reversible and competitive inhibitor of tryptophan hydroxylase (TPH), with a Ki of 32.6 μM . p-Ethynylphenylalanine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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1
1 Cited Publications
Cat. No.: HY-23460A
CAS No.: 188640-63-3
Synonyms: 4-Ethynyl-L-phenylalanine hydrochloride
Research Areas:  

Neurological Disease

p-Ethynylphenylalanine hydrochloride (4-Ethynyl-L-phenylalanine hydrochloride) is a potent, selective, reversible and competitive inhibitor of tryptophan hydroxylase (TPH), with a Ki of 32.6 μM . p-Ethynylphenylalanine (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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1
1 Cited Publications
Cat. No.: HY-P73733
Purity:  ≥ 95%, as determined by reducing SDS-PAGE or Bis-Tris PAGE.
Synonyms: PAH; PH; phenylalanine hydroxylase; L-phenylalanine hydroxylase; phenylalanine-4-hydroxylase; PAH Protein; Phe-4-Monooxygenase; PKU1; phenylalanine 4-Monooxygenase; PKU
Species:  
Human
Source:  
Sf9 insect cells
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Cat. No.: HY-W019599
CAS No.: 14173-39-8
Synonyms: L-PCPA
4-Chloro-L-phenylalanine (L-PCPA) is a tryptophan hydroxylase inhibitor targeting TPH1 and TPH2, with the activity of blocking serotonin biosynthesis. 4-Chloro-L-phenylalanine reduces the levels of serotonin and its metabolites in the brain without impairing the survival of serotonergic neurons. 4-Chloro-L-phenylalanine enhances anhedonic, depression-like and anxiety-like behaviors in mice with depleted noradrenergic and dopaminergic neurons. 4-Chloro-L-phenylalanine acts as a decarboxylation substrate for aromatic L-amino acid decarboxylase from Bacillus atrophaeus. 4-Chloro-L-phenylalanine can be used in studies related to Parkinson's disease .
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Cat. No.: HY-A0124AR
CAS No.: 69056-38-8
Synonyms: (6R)-BH4 dihydrochloride (Standard); (6R)-Tetrahydro-L-biopterin dihydrochloride (Standard)
Sapropterin ((6R)-BH4; (6R)-Tetrahydro-L-biopterin) dihydrochloride (Standard) is the analytical standard of Sapropterin dihydrochloride (HY-A0124A) . This product is intended for research and analytical applications. Sapropterin dihydrochloride is an orally active phenylalanine hydroxylase (PAH) cofactor, which is effective in reducing blood phenylalanine concentrations. Sapropterin dihydrochloride can be used in study of phenylketonuria (PKU) phenylketonuria. Sapropterin dihydrochloride can aggravate experimental autoimmune encephalomyelitis (EAE) .
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Cat. No.: HY-A0124
CAS No.: 62989-33-7
Synonyms: (6R)-BH4; (6R)-Tetrahydro-L-biopterin
Sapropterin ((6R)-BH4; (6R)-Tetrahydro-L-biopterin) is an orally active phenylalanine hydroxylase (PAH) cofactor, which is effective in reducing blood phenylalanine concentrations. Sapropterin can be used in study of phenylketonuria (PKU) phenylketonuria. Sapropterin can aggravate experimental autoimmune encephalomyelitis (EAE) .
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Cat. No.: HY-144856S1
CAS No.: 2747956-15-4
Synonyms: (6R)-BH4-d3; (6R)-Tetrahydro-L-biopterin-d3
Sapropterin-d3 ((6R)-BH4-d3) is deuterium labeled Sapropterin. Sapropterin ((6R)-BH4) is an orally active phenylalanine hydroxylase (PAH) cofactor, which is effective in reducing blood phenylalanine concentrations. Sapropterin can be used in study of phenylketonuria (PKU) .
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Cat. No.: HY-117551
CAS No.: 14231-41-5
Synonyms: NSC 524120
Research Areas:  

Metabolic Disease

Tetrahydroaminopterin (NSC 524120) is a tetrahydropteridine analog and the tetrahydro-reduced derivative of aminopterin. Tetrahydroaminopterin is used for studies on phenylalanine hydroxylase cofactor binding and the structure-activity relationship of tetrahydrobiopterin analogs .
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Cat. No.: HY-182578
CAS No.: 37053-15-9
Mimosinamine is a hydroxylase inhibitor with Fe 2+ chelating activity. Mimosinamine inhibits bovine adrenal tyrosine hydroxylase, rat liver phenylalanine hydroxylase, and rat brainstem tryptophan hydroxylase. Mimosinamine can be used in the research of hypertension .
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Cat. No.: HY-W071685
CAS No.: 945-43-7
Target:  

Endogenous Metabolite

Research Areas:  

Others

6, 7-dimethyl-5,6,7, 8-Tetrahydropterin hydrochloride is a synthetic analogue of tetrahydro-L-bioterin and is used as a cofactor required for the NOS isoforms, phenylalanine, tyrosine and tryptophan hydroxylases, and other enzymes .
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Cat. No.: HY-101456R
CAS No.: 14173-40-1
Synonyms: 4-Chloro-DL-phenylalanine methyl ester hydrochloride (Standard)
PCPA methyl ester (hydrochloride) (Standard) is the analytical standard of PCPA methyl ester (hydrochloride) (HY-101456). This product is intended for research and analytical applications. PCPA methyl ester hydrochloride (4-Chloro-DL-phenylalanine methyl ester hydrochloride), a reversible tryptophan hydroxylase inhibitor, is a serotonin (5-HT) synthesis inhibitor. PCPA methyl ester hydrochloride crosses the blood brain barrier and reduces 5-HT central availability .
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Cat. No.: HY-P4948
CAS No.: 1926163-49-6
Research Areas:  

Others

Coumarin-phalloidin is a kind of phalloidin labeled with Coumarin (HY-N0709). Coumarin-phalloidin is a new type of actin probe that can be used for triple immunofluorescence microscopic observation of the cell skeleton .
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