19 Results for "

pyridoxal-5'-phosphate

" in MedChemExpress (MCE) Product Catalog:
Products (19)

19 Results for "pyridoxal-5'-phosphate" in MCE Product Catalog:

5
5 Cited Publications
Cat. No.: HY-B1744
CAS No.: 54-47-7
Synonyms: pyridoxal 5′-phosphate; Pyridoxyl phosphate
Pyridoxal phosphate is the active form of vitamin B6, acts as an inhibitor of reverse transcriptases, and is used for the treatment of tardive dyskinesia.
loading...
    loading...
5
5 Cited Publications
Cat. No.: HY-W011727A
CAS No.: 41468-25-1
Synonyms: pyridoxal phosphate monohydrate
Pyridoxal 5'-phosphate monohydrate, the active form of vitamin B6, is an essential cofactor for multiple enzymes, including aromatic l-amino acid decarboxylase that catalyzes the final stage in the production of the neurotransmitters dopamine and serotonin. Pyridoxal 5'-phosphate monohydrate is the most important coenzyme variant in the process of vitamin B6 intracellular phosphorylation and is interconvertible with other variants, including pyridoxine 5′‐phosphate (PNP) and pyridoxamine 5′‐phosphate (PMP) .
loading...
    loading...
5
5 Cited Publications
Cat. No.: HY-W011727
CAS No.: 853645-22-4
Synonyms: pyridoxal phosphate hydrate
Pyridoxal 5'-phosphate hydrate, the active form of vitamin B6, is an essential cofactor for multiple enzymes, including aromatic l-amino acid decarboxylase that catalyzes the final stage in the production of the neurotransmitters dopamine and serotonin. Pyridoxal 5'-phosphate hydrate is the most important coenzyme variant in the process of vitamin B6 intracellular phosphorylation and is interconvertible with other variants, including pyridoxine 5′‐phosphate (PNP) and pyridoxamine 5′-phosphate (PMP) .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-N8157
CAS No.: 1464-33-1
4'-O-Methylpyridoxine is an orally active antivitamin B6 compound found in Ginkgo biloba seeds and leaves. 4'-O-Methylpyridoxine inhibits pyridoxal kinase. 4'-O-Methylpyridoxine reduces brain pyridoxal-5'-phosphate (PLP) levels, decreases gamma-aminobutyric acid/glutamate (GABA/Glu) ratio. 4'-O-Methylpyridoxine increases plasma levels of pyridoxal-5'-phosphate and pyridoxal. 4'-O-Methylpyridoxine induces hyperactivity, convulsions, pathological tissue changes, organ damage in rodent brain and heart .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-B1746
CAS No.: 529-96-4
Pyridoxamine 5′-phosphate is the active form of vitamin B6 bound to phosphoric acid. Pyridoxamine 5′-phosphate is the aminated form of Pyridoxal 5'-?phosphate monohydrate (HY-W011727A) and as co-factor of a variety of enzymes central metabolite, potent antioxidant, vitamin B6 vitamer and enzyme substrate. Pyridoxamine 5′-phosphate can be interconverted with pyridoxal 5'-phosphate hydrate .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-B1744R
CAS No.: 54-47-7
Synonyms: pyridoxal 5′-phosphate (Standard); Pyridoxyl phosphate (Standard)
Pyridoxal phosphate (Standard) is the analytical standard of Pyridoxal phosphate. This product is intended for research and analytical applications. Pyridoxal phosphate is the active form of vitamin B6, acts as an inhibitor of reverse transcriptases, and is used for the treatment of tardive dyskinesia.
loading...
    loading...
Cat. No.: HY-W011727S
CAS No.: 1354560-58-9
Synonyms: pyridoxal 5'-phosphate-d3
Pyridoxal Phosphate-d3 is the deuterium labeled Pyridoxal 5'-phosphate. Pyridoxal 5'-phosphate, the active form of vitamin B6, is an essential cofactor for multiple enzymes, including aromatic l-amino acid decarboxylase that catalyzes the final stage in the production of the neurotransmitters dopamine and serotonin. Pyridoxal 5'-phosphate is the most important coenzyme variant in the process of vitamin B6 intracellular phosphorylation and is interconvertible with other variants, including pyridoxine 5′‐phosphate (PNP) and pyridoxamine 5′-phosphate (PMP) .
loading...
    loading...
Cat. No.: HY-P991210
CAS No.: 2746354-58-3
Synonyms: ALXN-1850

Target:  

Phosphatase

Research Areas:  

Cardiovascular Disease

Efzimfotase alfa (ALXN-1850) is enzyme replacement therapy agent targeting the deficiency of tissue-nonspecific alkaline phosphatase (TNSALP). Efzimfotase alfa functions by hydrolyzing the substrates of TNSALP, reducing the concentrations of substrates such as inorganic pyrophosphate (PPi) and pyridoxal 5′-phosphate (PLP). Efzimfotase alfa is promising for research of hypophosphatasia (HPP) .
loading...
    loading...
Cat. No.: HY-W011727AR
CAS No.: 41468-25-1
Synonyms: pyridoxal phosphate monohydrate (Standard)
Pyridoxal 5'-​phosphate (monohydrate) (Standard) is the analytical standard of Pyridoxal 5'-​phosphate (monohydrate). This product is intended for research and analytical applications. Pyridoxal 5'-phosphate monohydrate, the active form of vitamin B6, is an essential cofactor for multiple enzymes, including aromatic l-amino acid decarboxylase that catalyzes the final stage in the production of the neurotransmitters dopamine and serotonin. Pyridoxal 5'-phosphate monohydrate is the most important coenzyme variant in the process of vitamin B6 intracellular phosphorylation and is interconvertible with other variants, including pyridoxine 5′‐phosphate (PNP) and pyridoxamine 5′-phosphate (PMP) .
loading...
    loading...
Cat. No.: HY-W745771
D-Penicillamine-d6 is the deuterium labeled L-Penicillamine (HY-116073). L-Penicillamine is a mechanism-based inhibitor of serine palmitoyltransferase by forming a pyridoxal-5 '-phosphate-thiazolidine adduct. L-Penicillamine is a metal chelating agent of intermediate strength .
loading...
    loading...
Cat. No.: HY-E70570
CAS No.: 9024-58-2
Target:  

GABA Receptor

Research Areas:  

Metabolic Disease

Glutamate decarboxylase is an enzyme that catalyzes the decarboxylation of glutamate to gamma-aminobutyric acid (GABA) and carbon dioxide (CO2). Many gut microbes can metabolize glutamate via their Glutamate decarboxylase in a pyridoxal-5′-phosphate (PLP) dependent manner .
loading...
    loading...
Cat. No.: HY-W011727R
CAS No.: 853645-22-4
Synonyms: pyridoxal phosphate hydrate (Standard)
Pyridoxal 5'-phosphate (hydrate) (Standard) is the analytical standard of Pyridoxal 5'-phosphate (hydrate) (HY-W011727). This product is intended for research and analytical applications. Pyridoxal 5'-phosphate hydrate, the active form of vitamin B6, is an essential cofactor for multiple enzymes, including aromatic l-amino acid decarboxylase that catalyzes the final stage in the production of the neurotransmitters dopamine and serotonin. Pyridoxal 5'-phosphate hydrate is the most important coenzyme variant in the process of vitamin B6 intracellular phosphorylation and is interconvertible with other variants, including pyridoxine 5′‐phosphate (PNP) and pyridoxamine 5′-phosphate (PMP) .
loading...
    loading...
Cat. No.: HY-162508
Target:  

Bacterial

Research Areas:  

Infection

KSK-104 has potent antibacterial activity against Mycobacterium tuberculosis (MIC=0.78 μM). The role of KSK-104 is mainly involved in the synthesis and recovery pathways of pyridoxal 5'-phosphate (PLP), PLP-dependent enzymes and oxidative stress networks. KSK-104, as a candidate molecule for novel anti-tuberculosis drugs, can be used to develop research against drug-resistant mycobacterium tuberculosis .
loading...
    loading...
Cat. No.: HY-162652
Target:  

Serine Racemase (SR)

Research Areas:  

Neurological Disease

HSR-IN-1 (Compound 28) is an effective hSR (human serine racemase) inhibitor. In the presence of the cofactor Pyridoxal 5'-phosphate monohydrate (HY-W011727A), HSR-IN-1 has a Kd value of 5.4 μM and an IC50 of 18.3 μM for hSR, while the IC50 of HSR-IN-1 alone is 4.7 μM. HSR-IN-1 can be used for research on central nervous system diseases .
loading...
    loading...
Cat. No.: HY-E71576
Research Areas:  

Others

2-Iminobutanoate/2-iminopropanoate deaminase (EC 3.5.99.10) catalyses the hydrolytic deamination of imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases; the reactions, which can occur spontaneously, are accelerated to minimize the cellular damage that could be caused by these reactive intermediates.
loading...
    loading...
Cat. No.: HY-E70894
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

α,γ-Homocysteinase, Trichomonas vaginalis is a pyridoxal-5’-phosphate dependent enzyme. α,γ-Homocysteinase, Trichomonas vaginalis is a mutant of homocysteinase from Trichomonas vaginalis encoded by mgl1 gene, containing three point mutations, such as; Phe47Leu, Asp172Glu, Ser308Tyr. α,γ-Homocysteinase, Trichomonas vaginalis can metabolize homocysteine into α-keto butyrate, hydrogen sulfide and ammonia.
loading...
    loading...
Cat. No.: HY-111598
CAS No.: 57229-25-1
Research Areas:  

Infection

4-Phospho-D-erythronate is a Ribose 5-phosphate isomerase inhibitor, intermediate in pyridoxal 5'-phosphate synthesis in some bacteria, and substrate for 4PE dehydrogenase (PdxB) in select proteobacteria .
loading...
    loading...
Cat. No.: HY-E71660
Research Areas:  

Others

3-Amino-5-hydroxybenzoate synthase (EC 4.2.1.144) is a pyridoxal 5'-phosphate-dependent enzyme involved in the biosynthetic pathway of Rifamycin B (HY-162836).
loading...
    loading...
Cat. No.: HY-E71076
Research Areas:  

Others

(5-Formylfuran-3-yl)methyl phosphate transaminase (EC 2.6.1.108), characterized from the archaebacterium Methanocaldococcus jannaschii, participates in the biosynthesis of the cofactor methanofuran. Requires pyridoxal 5'-phosphate.
loading...
    loading...
  • 1