2. Search Result
Search Result
Pathways Recommended: MAPK/ERK Pathway Neuronal Signaling JAK/STAT Signaling
Results for "

quorum-sensing signaling pathway

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

1

Peptides

1

Natural
Products

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P1934
    Cyclo(Phe-Pro)
    5+ Cited Publications

    Cyclo(phenylalanylprolyl); A-64863

    		 HCV Bacterial Antibiotic Reactive Oxygen Species (ROS) Infection
    Cyclo(Phe-Pro) (Cyclo(phenylalanylprolyl)) is a quorum-sensing molecule of Vibrio vulnificus that specifically interacts with RIG-I, inhibiting RIG-I polyubiquitination, suppressing IRF-3 activation, and reducing type I interferon production. Cyclo(Phe-Pro) enhances susceptibility to HCV and influenza virus and also alleviates plant aluminum toxicity stress. The mechanism of Cyclo(Phe-Pro) involves the regulation of host immune signaling pathways, bacterial virulence gene expression, and plant antioxidant systems, making it a promising candidate for research in viral infections, bacterial virulence regulation, and agricultural stress resistance .
    Cyclo(Phe-Pro)
  • HY-W008806
    N-(3-Oxohexanoyl)-L-homoserine lactone

    OHHL; N-(3-Oxohexanoyl)homoserine lactone

    		 Bacterial Infection Inflammation/Immunology
    N-(3-Oxohexanoyl)-L-homoserine lactone (OHHL; N-(3-Oxohexanoyl)homoserine lactone) is a specific agonist of LuxR-type transcription factor CarR with a Kd of 1.8 μM. N-(3-Oxohexanoyl)-L-homoserine lactone activates CarR by inducing protein multimerization, promoting its binding to target DNA sequences in the carR-carA intergenic region, thereby upregulating the transcription of carbapenem biosynthesis genes. N-(3-Oxohexanoyl)-L-homoserine lactone acts as a quorum sensing signal molecule, enabling bacteria to coordinate the production of carbapenem antibiotics in a cell density-dependent manner. N-(3-Oxohexanoyl)-L-homoserine lactone is used to study bacterial quorum sensing mechanisms, especially the secondary metabolism and virulence factor regulatory pathways of Erwinia carotovora and Yersinia enterocolitica .
    N-(3-Oxohexanoyl)-L-homoserine lactone
  • HY-126858
    Ambuic acid

    (+)-Ambuic acid

    		 ERK JNK NO Synthase COX Infection Inflammation/Immunology
    Ambuic acid exhibits antimicrobial activity against Staphylococcus aureus, with IC50 of 43.9 μM for strain ATCC 6538. Ambuic acid is an inhbitor for the biosynthesis of cyclic peptide quorum sensing molecules (quormones) in gram-positive bacteria. Ambuic acid exhibits anti-inflammatory activity through ERK/JNK/MAPK signaling pathway .
    Ambuic acid
  • HY-W554514
    D-Homoserine lactone

    		Bacterial Infection
    D-Homoserine lactone is a signaling molecule with the activity of regulating bacterial quorum sensing. The chemical structure of D-Homoserine lactone makes it a potential regulator of the AHL synthase RhlI. D-Homoserine lactone has been shown to inhibit the activity of RhlI, thereby affecting the bacterial quorum sensing signaling pathway. D-Homoserine lactone is also an enantiomer of L-homoserine lactone and is used as an inhibitor of serine hydroxymethyltransferase .
    D-Homoserine lactone
  • HY-W788542
    Quoromycin

    		Bacterial Infection
    Quoromycin is an orally active SmcR inhibitor with a Kd of 0.697 μM for Vibrio vulnificus SmcR. Quoromycin binds directly to SmcR, reduces its DNA-binding affinity, and inhibits the quorum sensing signaling pathway. Quoromycin is applicable to the research of Vibrio vulnificus infection .
    Quoromycin

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: