3 Results for "

rat BMSCs

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "rat BMSCs" in MCE Product Catalog:

2
Segetalin B
Segetalin B
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2 Cited Publications
Cat. No.: HY-107245
CAS No.: 164991-89-3
Purity:  99.51%
Category:  

Caryophyllaceae Extract Vaccaria segetalis (Neck.) Garcke Cyclopeptides Metabolic Disease Plants Disease Research Fields

Target:  

Estrogen Receptor/ERR Sirtuin RUNX

Segetalin B, an orally active cyclopentapeptide found in Vaccaria segetalis, possesses estrogen-like activity. Segetalin B promotes mineralization of ovariectomized rat-derived bone marrow mesenchymal stem cells (BMSCs) in vitro and increases the level of osteocalcin, BMP-2, ALP, and SIRT1 activity. Segetalin B is promising for research of post-menopausal osteoporosis (PMOP) .
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KLTWQELYQLKYKGI
KLTWQELYQLKYKGI
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Cat. No.: HY-P5558
CAS No.: 917760-16-8
Target:  

VEGFR

Research Areas:  

Neurological Disease

KLTWQELYQLKYKGI is a VEGF mimetic peptide designed based on the VEGF helix sequence 17-25, with the ability to activate VEGF receptors and exert pro-angiogenic biological activity. KLTWQELYQLKYKGI effectively promotes the attachment, spreading and proliferation of human umbilical vein endothelial cells. KLTWQELYQLKYKGI enhances the proliferation, migration and osteogenic differentiation of bone marrow stromal cells (BMSCs). KLTWQELYQLKYKGI synergistically accelerates angiogenesis and bone regeneration in rat cranial defect models. KLTWQELYQLKYKGI can be used for the research of brain tissue engineering and traumatic brain injury repair and biomaterials for bone tissue engineering and bone repair .
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TBE56
TBE56
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Cat. No.: HY-17655
Target:  

Molecular Glues Reactive Oxygen Species (ROS)

Research Areas:  

Inflammation/Immunology

TBE56, a molecular glue, is a BACH1 degrader, with an EC50 of 44 nM. TBE56 is a weak NRF2 inducer and the biotinylated TBE31. TBE56 interacts and promotes the degradation of BACH1 via a mechanism involving the E3 ligase FBX022. TBE56 reduces intracellular Fe 2+ accumulation, ROS generation, and malondialdehyde (MDA) content, while increasing GSH/GSSG ratio and upregulating GPX4 in Prominin-2-overexpressed BMSCs. TBE56 significantly ameliorates intervertebral disc degeneration (IVDD) in puncture-induced SD rat IVDD model. TBE56 can be used for the study of intervertebral disc degeneration (IVDD) .
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