9 Results for "

rat peritoneal leukocytes

" in MedChemExpress (MCE) Product Catalog:
Products (9)

9 Results for "rat peritoneal leukocytes" in MCE Product Catalog:

Cat. No.: HY-141570
CAS No.: 52691-62-0
Purity:  ≥98.0%
Target:  

Phospholipase

Research Areas:  

Others

Lyso-PAF C-16 is a precursor and metabolite of 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine (PAF C-16). Lyso-PAF C-16 is a substrate for either PAF C-16 formation by the remodeling pathway or selective acylation with arachidonic acid by a CoA-independent transacylase .
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Cat. No.: HY-141581
CAS No.: 74430-89-0
Purity:  ≥98.0%
Lyso-PAF C-18 is a single-chain ether phospholipid with membrane regulatory activity, and Lyso-PAF is the deacetylated inactive precursor of PAF. Lyso-PAF C-18 regulates the activity of plasma membrane Ca 2+-ATPase, and its mechanism of action may involve altering the lipid microenvironment of this enzyme. Lyso-PAF C-18 activates the calcium ATPase in rat synaptosomal membranes and inhibits the calcium ATPase in rat leukocyte membranes. Lyso-PAF C-18 can be used in cell membrane-related research .
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Cat. No.: HY-141570S
CAS No.: 201216-37-7
Purity:  ≥99.0%
Synonyms: Lyso-platelet-activating factor C-16-d4
Lyso-PAF C-16-d4 (Lyso-platelet-activating factor C-16-d4) is the deuterated-labeled Lyso-PAF C-16 (HY-141570). Lyso-PAF C-16 is a precursor and metabolite of 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine (PAF C-16). Lyso-PAF C-16 is a substrate for either PAF C-16 formation by the remodeling pathway or selective acylation with arachidonic acid by a CoA-independent transacylase .
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Cat. No.: HY-N11691
CAS No.: 67526-94-7
Synonyms: Thapsigargicine
Thapsigargicin (Thapsigargicine) is a activator of mast cells and leukocytes. Thapsigargicin induces histamine release from rat peritoneal mast cells and human basophil leukocytes. Thapsigargicin increases the cytoplasmic free calcium level in intact human blood platelets .
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Cat. No.: HY-167715
CAS No.: 58712-69-9
Traxanox is an orally available diuretic that enhances phagocytosis of yeast granules by mouse peritoneal macrophages and rat peritoneal polymorphonuclear leukocytes in vitro. Traxanox inhibits IgE-mediated histamine release and cyclic AMP phosphodiesterase activity.Traxanox exhibits anti-inflammatory activity, as it inhibits the anaphylactoid reaction and reduces pleural fluid accumulation in experimental models of inflammation. Traxanox also demonstrates a synergistic effect when combined with hydrocortisone or indomethacin in suppressing adjuvant arthritis in rats.
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Cat. No.: HY-141581S
Lyso-PAF C-18-d4 is the deuterated-labeled Lyso-PAF C-18 (HY-141581). Lyso-PAF C-18 is a single-chain ether phospholipid with membrane regulatory activity, and Lyso-PAF is the deacetylated inactive precursor of PAF. Lyso-PAF C-18 regulates the activity of plasma membrane Ca 2+-ATPase, and its mechanism of action may involve altering the lipid microenvironment of this enzyme. Lyso-PAF C-18 activates the calcium ATPase in rat synaptosomal membranes and inhibits the calcium ATPase in rat leukocyte membranes. Lyso-PAF C-18 can be used in cell membrane-related research .
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Cat. No.: HY-N19724
CAS No.: 62346-20-7
Buddledin A is a 5-LOX inhibitor (IC50 = 50.4 μM) and a COX inhibitor (IC50 = 13.7 μM). Buddedin A inhibits arachidonic acid metabolism via the 5-LOX and COX pathways, suppresses fungal growth, and exerts toxic effects on fish. Buddedin A may play an ecological role in protecting plant roots and stem barks from fungal infection. Buddedin A can be used in studies related to fungal infections .
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Cat. No.: HY-W747035
CAS No.: 33803-42-8
Gnaphaliin is a flavonoid compound that exerts antioxidant, anti-inflammatory, and tracheal smooth muscle relaxant effects by inhibiting lipid peroxidation, scavenging free radicals, chelating trace elements, and reducing neutrophil infiltration. Gnaphaliin can be used in research on asthma, inflammation, and atherosclerosis .
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Cat. No.: HY-19014
CAS No.: 83677-24-1
Target:  

Lipoxygenase COX

Research Areas:  

Inflammation/Immunology

KME-4 is an orally active dual inhibitor of 5-lipoxygenase (5-lipoxygenase) and cyclooxygenase (cyclooxygenase). KME-4 inhibits 5-lipoxygenase in the cytosol of guinea pig polymorphonuclear leukocytes (PMNL) and cyclooxygenase in rabbit platelets, with IC50 values of 0.85 μM and 0.44 μM, respectively. KME-4 can be used in studies related to arachidonic acid metabolism, inflammatory responses, and arthritis .
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