Thapsigargicin
Thapsigargicin (Thapsigargicine) is a activator of mast cells and leukocytes. Thapsigargicin induces histamine release from rat peritoneal mast cells and human basophil leukocytes. Thapsigargicin increases the cytoplasmic free calcium level in intact human blood platelets.
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- CAS No.: 67526-94-7
- Formula: C32H46O12
- Molecular Weight:622.70
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Chemical Information
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CAS No. 67526-94-7
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Molecular Weight 622.70
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Formula C32H46O12
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SMILES
CC1=C2[C@]([C@](C)(C[C@@H]([C@]3([C@@]2([H])OC([C@]3(O)C)=O)O)OC(CCC)=O)OC(C)=O)([H])[C@@H]([C@H]1OC(/C(C)=C\C)=O)OC(CCCCC)=O
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Synonyms
Thapsigargicine
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Ali H, et al. The ability of thapsigargin and thapsigargicin to activate cells involved in the inflammatory response. Br J Pharmacol. 1985 Jul;85(3):705-12. [Content Brief]
[2]. Khairy H, Adjei G, Allen-Redpath K, Scott RH. Actions of ethanolamine on cultured sensory neurones from neonatal rats. Neurosci Lett. 2010;468(3):326-329. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Thapsigargicin Related Classifications
HY-N11691 Related Classifications
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