Thapsigargicin
Based on 1 Customer Validation
Thapsigargicin (Thapsigargicine) is a activator of mast cells and leukocytes. Thapsigargicin induces histamine release from rat peritoneal mast cells and human basophil leukocytes. Thapsigargicin increases the cytoplasmic free calcium level in intact human blood platelets.
For research use only. We do not sell to patients.
- Purity : 99.36%
- CAS No.: 67526-94-7
- Formula: C32H46O12
- Molecular Weight:622.70
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Description
Chemical Information
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CAS No. 67526-94-7
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Appearance Solid
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Molecular Weight 622.70
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Formula C32H46O12
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SMILES
CC1=C2[C@]([C@](C)(C[C@@H]([C@]3([C@@]2([H])OC([C@]3(O)C)=O)O)OC(CCC)=O)OC(C)=O)([H])[C@@H]([C@H]1OC(/C(C)=C\C)=O)OC(CCCCC)=O
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Synonyms
Thapsigargicine
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (274 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
[1]. Ali H, et al. The ability of thapsigargin and thapsigargicin to activate cells involved in the inflammatory response. Br J Pharmacol. 1985 Jul;85(3):705-12. [Content Brief]
[2]. Khairy H, Adjei G, Allen-Redpath K, Scott RH. Actions of ethanolamine on cultured sensory neurones from neonatal rats. Neurosci Lett. 2010;468(3):326-329. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Thapsigargicin Related Classifications
HY-N11691 Related Classifications
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