Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
reduced-folate carrier
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "reduced-folate carrier" in MCE Product Catalog:
Synonyms: ZD 9331; BGC9331
Target:
Research Areas:
Plevitrexed (ZD 9331; BGC 9331) is an orally active and potent thymidylate synthase (TS) inhibitor with a Ki of 0.44 nM. Plevitrexed is taken up via the α-folate receptor as well as the reduced folate carrier. Plevitrexed is used for gastric cancer in clinical . Plevitrexed is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Synonyms: PT523
Research Areas:
Talotrexin (PT523), an analog of Aminopterin (HY-14518), is a nonpolyglutamatable classic antifolate. Talotrexin is a RFC (reduced folate carrier) specific inhibitor and selectively inhibits RFC transport. Talotrexin shows antitumor activity by targeting DHFR to inhibit tumor growth .
Cat. No.: HY-10824A
CAS No.: 648420-92-2
Synonyms: PT523 monoammonium
Research Areas:
Talotrexin monoammonium is the monoammonium salt form of Talotrexin (HY-10824). Talotrexin monoammonium is an analog of Aminopterin (HY-14518), and is a nonpolyglutamatable classic antifolate. Talotrexin monoammonium is a reduced folate carrier (RFC) specific inhibitor and selectively inhibits RFC transport. Talotrexin monoammonium shows antitumor activity by targeting DHFR to inhibit tumor growth .
Cat. No.: HY-P705625
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SLC19A1; Cyclic Dinucleotide:Anion Antiporter SLC19A1; Solute carrier Family 19 Member 1; reduced folate carrier Protein; IFC-1; Placental folate Transporter; RFT-1; reduced folate carrier 1; FOLT; folate Transporter 1; RFC1; HSLC19A1; HRFC; SLC19A1 Prote
Species:
Human
Source:
HEK293
Cat. No.: HY-P702013
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SLC19A2; Solute carrier Family 19 Member 2 Isoform 1; Prev. TRMA; reduced folate carrier Protein (RFC) Like; Thiamine Transporter 1; SLC19A2 Solute carrier Family 19 Member 2; ThTr-1; High Affinity Thiamine Transporter; THTR1; Thiamnine Trasporter Protein; ThT1; Thiamine Transporter THTR-1; Solute carrier Family 19 (Thiamine Transporter), Member 2; Thiamine carrier 1; Thiamine-Responsive Megaloblastic Anaemia; THMD1; TC1; ThTr1; Solute carrier Family 19 Thiamine Transporter Member 2; THT1; Solute carrier Family 19 Member 2; Solute carrier Family 19 Member 2 Isoform 2
Species:
Human
Source:
Sf9 insect cells
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
