4 Results for "

selenium-containing

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "selenium-containing" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-129960
CAS No.: 29621-88-3
Purity:  ≥97.0%
L-Selenocystine is a selenium-containing amino acid. L-Selenocystine has redox properties. L-Selenocystine is cytotoxic to various tumor cells and can induce the production of ROS and apoptosis. L-Selenocystine can block the Nrf2 and autophagy pathways. L-Selenocystine has anti-tumor activity .
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Cat. No.: HY-W585825
CAS No.: 2578-27-0
Target:  

Endogenous Metabolite

Research Areas:  

Others

Selenoethionine is a selenium-containing amino acid .
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Cat. No.: HY-184989
PD-L1-IN-12 is an orally active and potent selenium-containing small-molecule PD-L1 inhibitor (KD = 9.06 nM). PD-L1-IN-12 can mediate the internalization of PD-L1 and strongly block hPD-1 and hPD-L1 interaction (IC50 = 5.2 nM). PD-L1-IN-12 can be used in colorectal cancer immunology research .
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Cat. No.: HY-210765
CAS No.: 19192-78-0
Synonyms: SeOMet; SeMetO
Target:  

Drug Metabolite TrxR

Research Areas:  

Metabolic Disease

Selenomethionine selenoxide (SeOMet; SeMetO) is an oxidative metabolite of selenomethionine (SeMet). Selenomethionine selenoxide can be reduced by GSH to generate oxidized glutathione (GSSG) while regenerating the parent compound SeMet. Selenomethionine selenoxide can serve as a substrate for the thioredoxin reductase (TrxR) and glutathione reductase (GSR) systems in the presence of NADPH. Selenomethionine selenoxide can also be formed by the reaction of SeMet with N-chloramines, and the reduction of this substance supports the catalytic cycle by which selenium-containing compounds scavenge myeloperoxidase-derived oxidants. Selenomethionine selenoxide can be taken up by wheat roots and is converted to selenomethionine after root uptake. Selenomethionine selenoxide can be used in metabolism-related research .
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