149 Results for "

sn-Glycero-3-phosphocholine

" in MedChemExpress (MCE) Product Catalog:
Products (149)

149 Results for "sn-Glycero-3-phosphocholine" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-17552
CAS No.: 28319-77-9
Synonyms: Choline Alfoscerate; Alpha-GPC; L-α-GPC
sn-Glycero-3-phosphocholine (Choline Alfoscerate) is a precursor in the biosynthesis of brain phospholipids and increases the bioavailability of choline in nervous tissue. sn-Glycero-3-phosphocholine (Choline Alfoscerate) has significant effects on cognitive function with a good safety profile and tolerability, and is effective in the treatment of Alzheimer's disease and dementia .
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12
12 Publications Verification
Cat. No.: HY-113424A
CAS No.: 4235-95-4
Purity:  98.11%
Synonyms: DOPC
1,2-Dioleoyl-sn-glycero-3-phosphocholine (DOPC) is a phospholipid and is commonly used alone, or with other components, in the generation of micelles, liposomes, and other types of artificial membranes.
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3
3 Cited Publications
Cat. No.: HY-107737
CAS No.: 18194-25-7
Purity:  ≥98.0%
Synonyms: 1,2-Dilauroyl-sn-Glycero-3-phosphocholine
Research Areas:  

Metabolic Disease

1,2-DLPC (1,2-Dilauroyl-sn-glycero-3-phosphocholine) is a ligand for LRH-1 agonists. 1,2-DLPC is a phospholipid used in the synthesis of liposomes. 1,2-DLPC enhances fat breakdown and apoptosis in fat cells through a TNFα-dependent pathway, while also inhibiting palmitate-induced insulin resistance through PPARα-mediated inflammation in muscle cells [3].
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2
2 Cited Publications
Cat. No.: HY-125783
CAS No.: 17364-16-8
Purity:  99.92%
Synonyms: 16:0 Lyso PC
1-Palmitoyl-sn-glycero-3-phosphocholine (16:0 Lyso PC) is an abundant lysophosphatidylcholine. 1-Palmitoyl-sn-glycero-3-phosphocholine exhibits proinflammatory activity. 1-Palmitoyl-sn-glycero-3-phosphocholine can be used in the study of atherosclerosis [3] .
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2
2 Cited Publications
Cat. No.: HY-109541
CAS No.: 18194-24-6
Purity:  ≥98.0%
Synonyms: DMPC; 1,2-Dimyristoyl-sn-Glycero-3-phosphocholine; Dimyristoyl phosphatidylcholine
Target:  

Liposome

Research Areas:  

Cancer

Colfosceril miristate (DMPC) is a synthetic phospholipid. Colfosceril miristate has antiproliferative effects on various tumors. Colfosceril miristate is used to study lipid monolayers, bilayers and drug delivery [3].
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1
1 Cited Publications
Cat. No.: HY-125771
CAS No.: 19420-57-6
Purity:  99.53%
Synonyms: 18:0 Lyso-PC; LPC(18:0)
1-Stearoyl-sn-glycero-3-phosphocholine is a lysophosphatidylcholine that inhibits HDAC3 activity and phosphorylation of STAT3 in K562 cells. 1-Stearoyl-sn-glycero-3-phosphocholine induces apoptosis and exhibits anticancer activity in chronic myelogenous leukemia (CML) K562 cells .
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1
1 Cited Publications
Cat. No.: HY-W140439
CAS No.: 19420-56-5
Synonyms: 18:1 Lyso PC
Target:  

Endogenous Metabolite

Research Areas:  

Inflammation/Immunology

1-Oleoyl-sn-glycero-3-phosphocholine (18:1 Lyso PC), a lysophospholipid, is a GPR82 inhibitor. 1-Oleoyl-sn-glycero-3-phosphocholine abrogates constitutive Gi-coupled GPR82 activity, shifts active/inactive equilibrium to inactive, suppresses Gi protein activation, increases cAMP production, and decreases GTPγS binding to Gαi proteins. 1-Oleoyl-sn-glycero-3-phosphocholine contributes to adipocyte lipolysis regulation.1-Oleoyl-sn-glycero-3-phosphocholine exhibits reduced serum levels in mouse models of steatohepatitis, linked to hepatic Lpcat 1-4 up-regulation .
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Cat. No.: HY-177475
CAS No.: 60701-99-7
Synonyms: 1-Arachidonoyl-sn-Glycero-3-phosphocholine
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease Cancer

LysoPC 20:4 (20:4) (1-Arachidonoyl-sn-glycero-3-phosphocholine) is a serum metabolite. LysoPC 20:4 (20:4) decreases in tumor-bearing mice, but the reduction is not significant. LysoPC (20:4) can be used in cancer and obesity-related research .
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Cat. No.: HY-113010
CAS No.: 108341-80-6
Purity:  ≥99.0%
1-Arachidoyl-sn-glycero-3-phosphocholine is a lysophospholipid (LyP).
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Cat. No.: HY-W127499
CAS No.: 51779-95-4
Synonyms: DEPC; L-Dierucoyl lecithin; Dierucoyllecithin
Target:  

Liposome

Research Areas:  

Others

1,2-Dierucoyl-sn-glycero-3-phosphocholine (DEPC) is the composition of liposome membrane. 1,2-Dierucoyl-sn-glycero-3-phosphocholine is used for the preparation of liposomes and studying the properties of lipid bilayers. The GO (glucose oxidase) in the 1,2-Dierucoyl-sn-glycero-3-phosphocholine liposome shows the high activity .
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Cat. No.: HY-W013063
CAS No.: 998-06-1
Target:  

Liposome

Research Areas:  

Metabolic Disease

1,2-Dilinoleoyl-sn-glycero-3-phosphocholine is a phospholipid. 1,2-Dilinoleoyl-sn-glycero-3-phosphocholine can be used for obesity research .
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Cat. No.: HY-126356
CAS No.: 35418-59-8
1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine is a major phospholipid in low-density lipoprotein and belongs to the group of 1-acyl phosphatidylcholines. 1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine does not induce morphological changes in washed human platelets. 1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine can be used for the research of atherosclerosis and thrombotic diseases .
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Cat. No.: HY-W040255
CAS No.: 89947-79-5
Synonyms: PGPC
1-Palmitoyl-2-glutaryl-sn-glycero-3-phosphocholine is an oxidized phospholipid. 1-Palmitoyl-2-glutaryl-sn-glycero-3-phosphocholine reduces the viability of HUVECs, increases the levels of ferrous ions and lipid peroxidation, promotes the production of superoxide anions, and decreases the levels of glutathione and GPX4 in cells. 1-Palmitoyl-2-glutaryl-sn-glycero-3-phosphocholine upregulates the mRNA and protein levels of FABP3 in HUVECs, impairs mitochondrial membrane potential, and induces ferroptosis-related changes as well as mitochondrial dysfunction and damage. 1-Palmitoyl-2-glutaryl-sn-glycero-3-phosphocholine activates caspase-11 and promotes the continuous release of IL-1β from macrophages and dendritic cells. 1-Palmitoyl-2-glutaryl-sn-glycero-3-phosphocholine inhibits the proliferation of aortic smooth muscle cells and induces apoptosis in these cells. 1-Palmitoyl-2-glutaryl-sn-glycero-3-phosphocholine is applicable to relevant research on atherosclerosis [3] .
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Cat. No.: HY-17552R
CAS No.: 28319-77-9
Synonyms: Choline Alfoscerate (Standard); Alpha-GPC (Standard); L-α-GPC (Standard)
sn-Glycero-3-phosphocholine (Standard) is the analytical standard of sn-Glycero-3-phosphocholine. This product is intended for research and analytical applications. sn-Glycero-3-phosphocholine (Choline Alfoscerate) is a precursor in the biosynthesis of brain phospholipids and increases the bioavailability of choline in nervous tissue. sn-Glycero-3-phosphocholine (Choline Alfoscerate) has significant effects on cognitive function with a good safety profile and tolerability, and is effective in the treatment of Alzheimer's disease and dementia[1][2].
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Cat. No.: HY-142989
CAS No.: 99296-81-8
Purity:  97.3%
Target:  

Liposome HIV HCV HBV

Research Areas:  

Infection Cancer

1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine is a polyunsaturated phospholipid that serves as a component of lipid monolayers and small unilamellar vesicles. 1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine can be used to prepare endoplasmic reticulum-targeted liposomes (PERLs), which are composed of 1,2-didocosahexaenoyl-sn-glycero-3-phosphoethanolamine, l-α-phosphatidylinositol and l-α-phosphatidylserine at a molar ratio of 1.5:1.5:1:1. PERLs reduce cholesterol levels in human peripheral blood mononuclear cells (PBMCs) and decrease HIV-1 particle secretion from HIV-1-infected PBMCs. Liposomes formed from 1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine exhibit cytotoxicity against leukemia cells. 1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine is applicable to studies related to hepatitis C virus infection, HIV infection, hepatitis B virus infection and leukemia .
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Cat. No.: HY-W127457
CAS No.: 34506-67-7
Target:  

Liposome

Research Areas:  

Others

1,2-dihexanoyl-sn-glycero-3-phosphocholine is a phosphatidylcholine. It can play a role as a surfactant and is commonly used in the generation of micelles, liposomes, and other types of artificial membranes.
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Cat. No.: HY-126359
CAS No.: 27098-24-4
Purity:  ≥98.0%
Synonyms: SLPC; 18:0-18:2 PC
1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine (SLPC; 18:0-18:2 PC) is an endogenous phospholipid marker molecule in the glycerophospholipid metabolic pathway. 1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine is a core component of the phospholipid bilayer of biological membranes and a key responsive lipid for radiation injury and cardiometabolic diseases. 1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine constitutes the phospholipid bilayers of cell membranes and high-density lipoprotein (HDL), and regulates the core activity of lipoprotein functional homeostasis. The content of 1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine in mouse serum shows a significant dose-dependent decrease with increasing ionizing radiation dose, and its level in human HDL also decreases significantly in metabolic syndrome. 1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine can serve as a biological dosimeter marker for ionizing radiation injury, and is used for rapid and accurate assessment of radiation absorbed dose in exposed individuals. 1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine can also act as a lipidomics research target for cardiometabolic diseases such as lipid metabolic syndrome and early-onset coronary heart disease .
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Cat. No.: HY-122056
CAS No.: 39036-04-9
Synonyms: L-α-Diheptanoyllecithin; 12-Diheptanoyl-sn-Glycero-3-PC
Research Areas:  

Others

1,2-Diheptanoyl-SN-glycero-3-phosphocholine (L-α-Diheptanoyllecithin; 12-Diheptanoyl-sn-glycero-3-PC) is a short-chain phospholipid. 11,2-Diheptanoyl-SN-glycero-3-phosphocholine forms bimolecular micelles with long-chain phospholipids, and these micelles undergo adsorption and spontaneous fusion to generate supported lipid bilayers. 1,2-Diheptanoyl-SN-glycero-3-phosphocholine enhances the transdermal penetration of hydrophilic low-molecular-weight compounds via micellar pretreatment of the skin of hairless mice. 1,2-Diheptanoyl-SN-glycero-3-phosphocholine can be used in studies of membrane biology, structural biology and transdermal drug delivery .
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Cat. No.: HY-146794S
CAS No.: 2097561-16-3
1-Pentadecanoyl-2-oleoyl-sn-glycero-3-phosphocholine-d7 is deuterium labeled 1-Pentadecanoyl-2-oleoyl-sn-glycero-3-phosphocholine.
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Cat. No.: HY-141616
CAS No.: 50930-23-9
Purity:  ≥99.0%
1-Heptadecanoyl-2-hydroxy-sn-glycero-3-phosphocholine is an endogenous metabolite present in Blood that can be used for the research of Pregnancy and Sepsis [3].
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