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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
40 Results for "
uPAR
" in MedChemExpress (MCE) Product Catalog:
Products (40)
40 Results for "uPAR" in MCE Product Catalog:
3
3 Cited Publications
Target:
Áreas de investigación:
IPR-803 is a potent inhibitor of the uPAR·uPA protein-protein interaction (PPI). IPR-803 binds directly to uPAR with sub-micromolar affinity. IPR-803 displays anti-tumor activity .
2
Referencia número: HY-P11446
No. CAS: 254729-66-3
Target:
Áreas de investigación:
Referencia número: HY-P990552A
Referencia número: HY-P5018
No. CAS: 1820563-84-5
Target:
Áreas de investigación:
NOTA-AE105 is a uPAR-targeting PET imaging ligand. NOTA-AE105 can be radiolabeled with 64Cu and 68Ga. NOTA-AE105 binds to the urokinase-type plasminogen activator receptor, thereby enabling PET imaging of uPAR expression in tumor tissues. NOTA-AE105 can be used for research on head and neck squamous cell carcinoma, breast cancer, prostate cancer, bladder cancer, and glioblastoma .
Referencia número: HY-P1615
No. CAS: 1006388-38-0
Synonyms: uPARANT
Target:
Transmembrane Glycoprotein Formyl Peptide Receptor (FPR) VEGFR Akt STAT JNK p38 MAPK ERK NF-κB Apoptosis Integrin
Áreas de investigación:
Cardiovascular Disease Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Category:
Target:
Referencia número: HY-RS10648
Target:
Áreas de investigación:
PLAUR Human Pre-designed siRNA Set A contains three designed siRNAs for PLAUR gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Referencia número: HY-P990552
Target:
Áreas de investigación:
Referencia número: HY-P11023
Target:
Áreas de investigación:
Referencia número: HY-P11446A
Target:
Áreas de investigación:
Referencia número: HY-RS17422
Target:
Áreas de investigación:
Plaur Mouse Pre-designed siRNA Set A contains three designed siRNAs for Plaur gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Referencia número: HY-P11413
No. CAS: 139446-70-1
Áreas de investigación:
Cardiovascular Disease Metabolic Disease Inflammation/Immunology
PAI-1 is a serine protease inhibitor (SERPIN). PAI-1 binds to and irreversibly inhibits uPA, tPA and furin; it also interacts with vitronectin, α1-acid glycoprotein, CRT, TLR4, proteasome α-3 subunit, uPAR, LRP1, Integrin αvβ3 and thrombin. PAI-1 regulates fibrinolysis, extracellular matrix turnover, cell migration, angiogenesis, inflammatory response and tissue remodeling; it mediates epithelial-mesenchymal transition (EMT)/endothelial-mesenchymal transition (EndMT), apoptosis and thrombus stabilization. PAI-1 can be used in research related to sepsis, acute lung injury, cardiovascular diseases, tissue fibrosis, diabetic nephropathy, obstructive nephropathy and non-insulin-dependent diabetes mellitus .
Referencia número: HY-RS24858
Target:
Áreas de investigación:
Cadm4 Rat Pre-designed siRNA Set A contains three designed siRNAs for Cadm4 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Referencia número: HY-RS23877
Target:
Áreas de investigación:
Plaur Rat Pre-designed siRNA Set A contains three designed siRNAs for Plaur gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Referencia número: HY-P81512A
Synonyms: U-PAR; Monocyte activation antigen Mo3; CD87
Referencia número: HY-P700849
Pureza: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PLAUR; Monocyte Activation Antigen Mo3; Plasminogen Activator, Urokinase Receptor; U-PAR; Urokinase Plasminogen Activator Surface Receptor; Urokinase Plasminogen Activator Receptor; uPAR; U-Plasminogen Activator Receptor Form 2; URKR; CD87 Antigen; CD87;
Species:
Mouse
Source:
HEK293
Referencia número: HY-P704953
Pureza: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PLAUR; Monocyte Activation Antigen Mo3; Plasminogen Activator, Urokinase Receptor; U-PAR; Urokinase Plasminogen Activator Surface Receptor; Urokinase Plasminogen Activator Receptor; uPAR; U-Plasminogen Activator Receptor Form 2; URKR; CD87 Antigen; CD87;
Species:
Cynomolgus
Source:
HEK293
Referencia número: HY-P704954
Pureza: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: PLAUR; Monocyte Activation Antigen Mo3; Plasminogen Activator, Urokinase Receptor; U-PAR; Urokinase Plasminogen Activator Surface Receptor; Urokinase Plasminogen Activator Receptor; uPAR; U-Plasminogen Activator Receptor Form 2; URKR; CD87 Antigen; CD87;
Species:
Human
Source:
HEK293
Referencia número: HY-P704957
Pureza: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PLAUR; Monocyte Activation Antigen Mo3; Plasminogen Activator, Urokinase Receptor; U-PAR; Urokinase Plasminogen Activator Surface Receptor; Urokinase Plasminogen Activator Receptor; uPAR; U-Plasminogen Activator Receptor Form 2; URKR; CD87 Antigen; CD87;
Species:
Mouse
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
