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ultrastructure

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7

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Click Chemistry

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W353469

    Glucosylglycerol

    Biochemical Assay Reagents Others
    2-O-(α-D-Glucopyranosyl) glycerol (55% in water) (Glucosylglycerol) is a glycerol glycoside and compatible solute. 2-O-(α-D-Glucopyranosyl) glycerol is isolable from the marine cyanobacterium Oscillatoria sp. 2-O-(α-D-Glucopyranosyl) glycerol (55% in water) acts as a salt stress protectant in Synechocystis sp. PCC 6803 ΔggpS cells. It enhances salt tolerance of Synechocystis sp. PCC 6803 ΔggpS cells and maintains cell division under salt stress .
    2-O-(α-D-Glucopyranosyl)glycerol (55% in water)
  • HY-P10932

    Fluorescent Dye Neurological Disease
    pGk13a is an amphipathic membrane-labeling probe containing an azide group, which can bind to fluorophores. pGk13a enables high-resolution imaging of cell membranes in the ultrastructure expansion microscopy (umExM) technique, facilitating the observation of membrane-associated structures and proteins. pGk13a is applicable to neuronal structure research .
    pGk13a
  • HY-136674

    Amyloid-β Neurological Disease
    Aftin-5 is an inducer for Amyloid-β 42 (Aβ42). Aftin-5 upregulates Aβ42 and downregulates Aβ38 levels in a β-secretase- and γ-secretase-dependent manner by altering the ultrastructure of mitochondria. Aftin-5 exhibits slightly cytotoxicity in cell SH-SY5Y, HT22, N2a and N2a-AβPP695, with IC50s of 180, 194, 178 and 150 μM, respectively .
    Aftin-5
  • HY-122029

    Mitochondrial Metabolism Metabolic Disease
    BRD6897 is a mitochondrial content inducer. BRD6897 does not alter the percent of cytoplasmic area occupied by mitochondria, but instead, induces a striking increase in the electron density of existing mitochondria .
    BRD6897
  • HY-149614

    Endogenous Metabolite Fungal Infection
    Laccase-IN-1 (compound 4b) is an orally active inhibitor of laccase, with the IC50 of 11.3 μM. Laccase-IN-1 displays protective and curative effects on apple fruits infected by B. dothidea. Laccase-IN-1 enhances the cell membrane permeability, destroys the mycelial surface morphology and the cell ultrastructure, and reduces the ergosterol and exopolysaccharide contents of B. dothidea .
    Laccase-IN-1
  • HY-123746

    Farnesyl Transferase Fungal Parasite Infection
    E5700 is an orally active squalene synthase inhibitor, antimalarial agent and antifungal agent with an IC50 of 0.49 nM (without PPi) against squalene synthase from T. cruzi epimastigotes. E5700 shows antiparasitic activities against Trypanosoma cruzi. E5700 inhibits the growth and alters the lipid prolife and the ultrastructure of a multiple agent-resistant C. tropicalis strain. E5700 is a potent and selective inhibitor of the growth of Leishmania amazonensis .
    E5700
  • HY-181672

    PI3K Akt ERK Epigenetic Reader Domain Neurological Disease
    PI3K/AKT/ERK/CREB activator 1 is an orally active PI3K/AKT/ERK/CREB pathway activator. PI3K/AKT/ERK/CREB activator 1 maintains neuronal survival and function, promotes neuronal proliferation, restores the viability of damaged neurons, and facilitates synapse formation. PI3K/AKT/ERK/CREB activator 1 alleviates neuroinflammation by reducing the levels of pro-inflammatory cytokines, preserves synaptic ultrastructure and restores spatial memory in Alzheimer's disease models. PI3K/AKT/ERK/CREB activator 1 can be used in research related to Alzheimer's disease .
    PI3K/AKT/ERK/CREB activator 1

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