Lexaptepid Pegol
Lexaptepid Pegol is a pegylated structured L-oligoribonucleotide. It binds and inhibits hepcidin.
For research use only. We do not sell to patients.
- CAS No.: 1390631-57-8
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 1390631-57-8
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SMILES
[Lexaptepid Pegol]
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Synonyms
NOX-H94
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Boyce M, Warrington S, Cortezi B, et al. Safety, pharmacokinetics and pharmacodynamics of the anti-hepcidin Spiegelmer lexaptepid pegol in healthy subjects. Br J Pharmacol. 2016;173(10):1580-1588. [Content Brief]
[2]. Schwoebel F, van Eijk LT, Zboralski D, et al. The effects of the anti-hepcidin Spiegelmer NOX-H94 on inflammation-induced anemia in cynomolgus monkeys. Blood. 2013;121(12):2311-2315. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)