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Cat. No.: HY-125490

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Shermilamine B

(Synonyms: Debromoshermilamine A)

Shermilamine B, a pyridoacridine alkaloid, exhibits potent anticancer activity in multiple myeloma cell lines.

For research use only. We do not sell to patients.

CAS No.: 122271-41-4
Formula: C₂₁H₁₈N₄O₂S
Molecular Weight:390.46

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Shermilamine B Chemical Structure

CAS No.: 122271-41-4

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Shermilamine B, a pyridoacridine alkaloid, exhibits potent anticancer activity in multiple myeloma cell lines^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
HCT-116	IC₅₀	13.8 μM Compound: 6	Tested for the cytotoxicity to inhibit replication assay against the human colon tumor cell line HCT116 Tested for the cytotoxicity to inhibit replication assay against the human colon tumor cell line HCT116	[PMID: 7525959]

Chemical Information

CAS No. 122271-41-4
Molecular Weight 390.46
Formula C₂₁H₁₈N₄O₂S
SMILES

O=C(C)NCCC1=C2SCC(NC2=C3N=CC=C4C5=C(NC1=C34)C=CC=C5)=O
Synonyms

Debromoshermilamine A
Structure Classification
- Alkaloids
- Other Alkaloids
Initial Source
- Microorganisms
Tunicate Eudistoma sp.
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Pedro Jatai Batista, et al. Chemical and Pharmacological Prospection of the Ascidian Cystodytes dellechiajei. Mar Drugs. 2024 Jan 31;22(2):75. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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