SHP2-IN-27
SHP2-IN-27 (compound 28) is an allosteric inhibitor of tyrosine phosphatase SH2.
For research use only. We do not sell to patients.
- CAS No.: 2376012-00-7
- Formula: C21H22ClN7
- Molecular Weight:407.90
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HCC827 | IC50 |
2.1 μM
Compound: 28
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Antiproliferative activity against human HCC827 cells harboring EGFR del 746 to 750 mutant assessed as inhibition of cell growth incubated for 6 days by celltiter-glo luminescence based analysis
Antiproliferative activity against human HCC827 cells harboring EGFR del 746 to 750 mutant assessed as inhibition of cell growth incubated for 6 days by celltiter-glo luminescence based analysis
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[PMID: 38462716] |
Chemical Information
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CAS No. 2376012-00-7
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Molecular Weight 407.90
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Formula C21H22ClN7
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SMILES
N[C@H](C[C@@H]1CC2)C[C@@H]2N1C3=CN=C4C(NC=C4C5=C(Cl)C6=CN(C)N=C6C=C5)=N3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SHP2-IN-27 Related Classifications
HY-162355 Related Classifications
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