Sodium Citrate Buffer, 0.1M, pH 4.0
Based on 10 publication(s) in Google Scholar
Sodium Citrate Buffer, 0.1M, pH 4.0 is an acidic, aqueous buffer solution. Sodium Citrate Buffer, 0.1M, pH 4.0 resists pH fluctuations, chelates metal ions, and regulates the redox potential of the system. Sodium Citrate Buffer, 0.1M, pH 4.0 is widely used in molecular biology, immunohistochemistry (IHC), and biochemistry.
For research use only. We do not sell to patients.
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications Citing Use of MedChemExpress (MCE) Sodium Citrate Buffer, 0.1M, pH 4.0
More- Bone Res. 2025 Mar 3;13(1):30. [Abstract]
- Autophagy. 2026 Jun 10:1-23. [Abstract]
- Autophagy. 2026 Apr 29. [Abstract]
- ACS Nano. 2025 Aug 25. [Abstract]
- Cancer Lett. 2024 May 28:590:216845. [Abstract]
- Int J Biol Macromol. 2026 Mar:350:150917. [Abstract]
- Life Sci. 2025 Sep 1:376:123746. [Abstract]
- Mol Immunol. 2026 Feb:190:1-10. [Abstract]
- Diabetes Metab Syndr Obes. 2025 Jun 28:18:2041-2055. [Abstract]
- bioRxiv. 2026 Mar 21:2026.03.20.712457. [Abstract]
Biological Activity
Sodium Citrate Buffer, 0.1M, pH 4.0 is applied in heat-induced epitope retrieval (HIER) to reverse antigenicity loss in Formalin-fixed paraffin-embedded tissues by breaking protein cross-links, thereby unmasking antigens and epitopes and ultimately enhancing antibody staining intensity[2][3].
Sodium Citrate Buffer, 0.1M, pH 4.0 can be used as a stabilizer to stabilize proteins and enzymes, hydrate liposomes, and reverse antigen cross-linking[2][3].
Sodium Citrate Buffer, 0.1M, pH 4.0 is widely used in buffer preparation[2].
Sodium Citrate Buffer, 0.1M, pH 4.0 can be used as an RT-PCR enhancement reagent[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Liquid
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Color Colorless to light yellow
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SMILES
[Sodium Citrate Buffer, 0.1M, pH 4.0]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (10)
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Journal Impact Factor
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Most Recent
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Bone Res
Enhanced SIRT3 expression restores mitochondrial quality control mechanism to reverse osteogenic impairment in type 2 diabetes mellitus. [Abstract]2025 Mar 3;13(1):30. PMID: 40025004 -
Autophagy
MEN1/menin deficiency suppresses hepatocellular carcinogenesis via disrupting mitophagy-mediated mitochondrial homeostasis. [Abstract]2026 Jun 10:1-23. PMID: 42210578 -
Autophagy
Cardiac fibroblast-derived CCN1 aggravates diabetic cardiomyopathy through ITGAV-ITGB1/integrin αvβ1-mediated autophagy inhibition. [Abstract]2026 Apr 29. PMID: 42056922 -
ACS Nano
Dual-Targeting Mn@CeO2 Nanozyme-Modified Probiotic Hydrogel Microspheres Reshape Gut Homeostasis in Inflammatory Bowel Disease. [Abstract]2025 Aug 25. PMID: 40853091 -
Cancer Lett
CAPN2-responsive mesoporous silica nanoparticles: A promising nanocarrier for targeted therapy of pancreatic cancer. [Abstract]2024 May 28:590:216845. PMID: 38589004 -
Int J Biol Macromol
ETS transcription factor 1-insulin-like growth factor 2 mRNA-binding protein 2-interferon-induced transmembrane protein 3 pathway promotes ferroptosis-driven osteoblast senescence in diabetic osteoporosis. [Abstract]2026 Mar:350:150917. PMID: 41692190 -
Life Sci
KAT2A-mediated H3K79 succinylation promotes ferroptosis in diabetic nephropathy by regulating SAT2. [Abstract]2025 Sep 1:376:123746. PMID: 40409584 -
Mol Immunol
Formononetin in Jiawei Qihuangyin inhibits podocyte epithelial-mesenchymal transition and ameliorates diabetic nephropathy via SIRT1/NF-κB axis. [Abstract]2026 Feb:190:1-10. PMID: 41483656 -
Diabetes Metab Syndr Obes
Yiqi Yangyin Tongluo Recipe Alleviates Diabetic Kidney Disease Through AGE-RAGE Signalling Axis. [Abstract]2025 Jun 28:18:2041-2055. PMID: 40606302 -
bioRxiv
Structure-Activity Mapping of Intraperitoneal mRNA-LNPs: Decoupling Tumor and Liver Biodistribution in Pancreatic Cancer. [Abstract]2026 Mar 21:2026.03.20.712457. PMID: 41889911
Purity & Documentation
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Data Sheet (267 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
[1]. L M Sammel, et al. Investigation of mechanisms by which sodium citrate reduces the pink color defect in cooked ground turkey. Meat Sci. 2006, 72, 4. [Content Brief]
[2]. Huang C, e al., Liver-Specific Ionizable Lipid Nanoparticles Mediated Efficient RNA Interference to Clear "Bad Cholesterol". Int J Nanomedicine. 2023 Dec 19;18:7785-7801. [Content Brief]
[3]. Liu Y, et al. Immobilization of laccase on magnetic bimodal mesoporous carbon and the application in the removal of phenolic compounds. Bioresour Technol. 2012 Jul;115:21-6. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)