2. Metabolic Enzyme/Protease
  3. Steroid Sulfatase
  4. Steroid sulfatase-IN-2

Steroid sulfatase -IN-2 is an active steroid sulfatase (STS) inhibitor with an IC50 value of 109.5 nM. Steroid sulfatase-IN-2 can be used for the research of hormone-dependent cancers, such as estrogen-dependent breast and endometrial cancer.

For research use only. We do not sell to patients.

Steroid sulfatase-IN-2 Chemical Structure

Steroid sulfatase-IN-2 Chemical Structure

CAS No. : 2413880-39-2

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Steroid sulfatase-IN-2 Related Antibodies

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Description

Steroid sulfatase -IN-2 is an active steroid sulfatase (STS) inhibitor with an IC50 value of 109.5 nM. Steroid sulfatase-IN-2 can be used for the research of hormone-dependent cancers, such as estrogen-dependent breast and endometrial cancer[1].

IC50 & Target

IC50：109.5 nM (STS)[1]
In Vitro

Steroid sulfatase-IN-2 (compound 1h, 0.001-10 μM, 1 h) inhibits STS in the lysate of JEG-3 cells, with an IC50 value of 109.5 nM[1].
Steroid sulfatase-IN-2 (1-1 μM, 20 h) inhibits STS in a whole-cell assay against JEG-3 cells, with an IC50 value of 13.6 nM[1].
Steroid sulfatase-IN-2 (0.01-100 μM, 5 days) shows dose-dependent antiproliferative activity against T-47D estrogen-dependent breast cancer cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Steroid sulfatase-IN-2 Related Antibodies

Cell Viability Assay[1]

Cell Line: T-47D cells
Concentration: 0.01-100 μM
Incubation Time: 5 days
Result: Inhibited cell proliferation with an IC50 value of 5.78 μM.
Molecular Weight

350.43

Formula

C17H22N2O4S
CAS No.
SMILES

O=C(C12CC3CC(C2)CC(C1)C3)NC4=CC=C(C=C4)OS(=O)(N)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Steroid sulfatase-IN-2 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Steroid sulfatase-IN-22413880-39-2Steroid SulfataseSTS inhibitionJEG-3T-47DproliferationhormonecancerInhibitorinhibitorinhibit

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