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Cat. No.: HY-105829

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Sulfatroxazole

Name: Sulfatroxazole
Brand: MedChemExpress
SKU: HY-105829
Price: 134.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(Synonyms: Isosulfafurazole)

Sulfatroxazole (Isosulfafurazole) (compound 12) is a selective antagonist of ETA receptor (IC₅₀=0.26 μM).

For research use only. We do not sell to patients.

CAS No.: 23256-23-7
Formula: C₁₁H₁₃N₃O₃S
Molecular Weight:267.30

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

Sulfatroxazole Chemical Structure

CAS No.: 23256-23-7

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Protocols (1)
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Sulfatroxazole (Isosulfafurazole) (compound 12) is a selective antagonist of ETA receptor (IC₅₀=0.26 μM)^[1].

All Endothelin Receptor Isoforms :

ET_A
ET_B

Cellular Effect

Cell Line	Type	Value	Description	References
A7R5	IC₅₀	5 μM Compound: 5d	Displacement of [125 I] ET-1 from rat aortic smooth muscle A7r5 cells transfected with Endothelin A receptor Displacement of [125 I] ET-1 from rat aortic smooth muscle A7r5 cells transfected with Endothelin A receptor	[PMID: 10969989]

Chemical Information

CAS No. 23256-23-7
Molecular Weight 267.30
Formula C₁₁H₁₃N₃O₃S
SMILES

O=S(NC1=NOC(C)=C1C)(C2=CC=C(C=C2)N)=O
Synonyms

Isosulfafurazole
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocols

All Cell Biology

Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Stein P D, et al. Discovery and structure-activity relationships of sulfonamide ETA-selective antagonists[J]. Journal of medicinal chemistry, 1995, 38(8): 1344-1354. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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100 mg

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