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United States

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Cat. No.: HY-162991

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TCO-PAL-PARP

TCO-PAL-PARP is a PARP PAL probe modified with a trans-cyclooctene group, which can be utilized in live cells.

For research use only. We do not sell to patients.

Formula: C₄₁H₄₄N₁₀O₅
Molecular Weight:756.85

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (263 KB)

TCO-PAL-PARP Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

TCO-PAL-PARP is a PARP PAL probe modified with a trans-cyclooctene group, which can be utilized in live cells^[1].

Chemical Information

Molecular Weight 756.85
Formula C₄₁H₄₄N₁₀O₅
SMILES

O=C(O[C@H]1CC/C=C/CCC1)NCCC2(CCC(NC3=CC(C#N)=C(N4CCN(C(C5=CC=CC(CC6=NNC(C7=C6C=CC=C7)=O)=C5)=O)CC4)N=C3)=O)N=N2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (263 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Rutkowska A, et al. Synergistic effects of PARP inhibition and cholesterol biosynthesis pathway modulation[J]. Cancer Research Communications, 2024, 4(9): 2427-2443. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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