TCO-PEG11-TCO
TCO-PEG11-TCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. TCO-PEG11-TCO is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
For research use only. We do not sell to patients.
- Formula: C42H76N2O15
- Molecular Weight:849.06
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All PROTAC Linkers Isoforms
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Biological Activity
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 849.06
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Formula C42H76N2O15
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SMILES
O=C(O[C@H]1CCC/C([H])=C/CC1)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(O[C@H]2CCC/C([H])=C/CC2)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)