TD-6450
TD-6450 (Compound 51) is an orally active HCV 1A inhibitor. TD-6450 inhibits the pan-genotypic nonstructural protein 5A (NS5A). TD-6450 can be used for research on diseases such as hepatitis.
For research use only. We do not sell to patients.
- CAS No.: 1374883-22-3
- Formula: C41H48F3N9O6
- Molecular Weight:819.87
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 1374883-22-3
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Molecular Weight 819.87
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Formula C41H48F3N9O6
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SMILES
COC(N[C@@H](C(C)C)C(N1[C@H](C(N2)=NC=C2C(C=C3)=CC=C3C4=C(OC(F)(F)F)C=C(NC(C5=CN=C(C=C5)N6C[C@@H](N(C[C@H]6C)C(NC)=O)C)=O)C=C4)CCC1)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Belema M, et al. Discovery and development of hepatitis C virus NS5A replication complex inhibitors. J Med Chem. 2014 Mar 13;57(5):1643-72. [Content Brief]
[2]. Carucci M, et al. Safe drugs with high potential to block malaria transmission revealed by a spleen-mimetic screening. Nat Commun. 2023 Apr 7;14(1):1951. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)