Thalidomide-5-NH-C-alkyne
Based on 1 Customer Validation
Thalidomide-5-NH-C-alkyne contains an E3 ligase ligand with a terminal alkyne. Thalidomide-5-NH-C-alkyne is ready for conjugation to target proteins for PROTAC.
For research use only. We do not sell to patients.
- Purity : 98.0%
- CAS No.: 2357110-24-6
- Formula: C16H13N3O4
- Molecular Weight:311.30
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
All E3 Ligase Ligand-Linker Conjugates Isoforms
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Biological Activity
Description
Chemical Information
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CAS No. 2357110-24-6
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Appearance Solid
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Molecular Weight 311.30
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Formula C16H13N3O4
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Color Light yellow to brown
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SMILES
O=C1N(C(C2=C1C=CC(NCC#C)=C2)=O)C3CCC(NC3=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 50 mg/mL (160.62 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (242 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.2123 mL | 16.0617 mL | 32.1234 mL | 80.3084 mL |
| 5 mM | 0.6425 mL | 3.2123 mL | 6.4247 mL | 16.0617 mL | |
| 10 mM | 0.3212 mL | 1.6062 mL | 3.2123 mL | 8.0308 mL | |
| 15 mM | 0.2142 mL | 1.0708 mL | 2.1416 mL | 5.3539 mL | |
| 20 mM | 0.1606 mL | 0.8031 mL | 1.6062 mL | 4.0154 mL | |
| 25 mM | 0.1285 mL | 0.6425 mL | 1.2849 mL | 3.2123 mL | |
| 30 mM | 0.1071 mL | 0.5354 mL | 1.0708 mL | 2.6769 mL | |
| 40 mM | 0.0803 mL | 0.4015 mL | 0.8031 mL | 2.0077 mL | |
| 50 mM | 0.0642 mL | 0.3212 mL | 0.6425 mL | 1.6062 mL | |
| 60 mM | 0.0535 mL | 0.2677 mL | 0.5354 mL | 1.3385 mL | |
| 80 mM | 0.0402 mL | 0.2008 mL | 0.4015 mL | 1.0039 mL | |
| 100 mM | 0.0321 mL | 0.1606 mL | 0.3212 mL | 0.8031 mL |
Thalidomide-5-NH-C-alkyne Related Classifications
HY-W674324 Related Classifications
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