TnGalNAc-T
Based on 1 Customer Validation
TnGalNAc-T is an N-acetylgalactosaminyltransferase from Trichoplusia ni that catalyzes the attachment of a UDP-activated azide-modified N-acetylgalactosamine monosaccharide to a core GlcNAc residue via a beta(1,4) bond-forming reaction. His-tagged TnGalNAc-T can be expressed from mammalian cells and purified in high isolated yields using Ni Sepharose Excel with no need for refolding from inclusion bodies.
For research use only. We do not sell to patients.
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
TnGalNAc-T enables site-specific antibody conjugation by mediating the attachment of an azide-modified GalNAc to a core GlcNAc residue on homogenised mAbs, and can be expressed and purified in high yields from mammalian cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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SMILES
[TnGalNAc-T]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
TnGalNAc-T Related Classifications
HY-E72118 Related Classifications
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Keywords
- TnGalNAc-T
- Glycosyltransferase
- mammalian cells
- N-acetylgalactosaminyltransferase
- Trichoplusia ni
- Ni Sepharose Excel
- UDP-activated azide-modified N-acetylgalactosamine monosaccharide
- beta(1,4) bond-forming reaction
- core GlcNAc residue
- site-specific antibody conjugation
- His-tagged TnGalNAc-T
- Inhibitor
- inhibitor
- inhibit