Tri-GalNAc-NH2
Tri-GalNAc-NH2 is a synthetic tri-N-acetylgalactosamine ligand that targets the asialoglycoprotein receptor (ASGPR). Tri-GalNAc-NH2 can be used as an intermediate for constructing LYTAC antibody-ligand conjugates.
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- CAS No.: 1646198-77-7
- 화학식: C67H121N11O28
- 분자량:1528.75
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
제품 설명
In Vitro
Tri-GalNAc-NH2 (compound 6) can be used as an intermediate to react and generate Tri-GalNAc-DBCO (compound 7), and antibody conjugates carrying the Tri-GalNAc ligand mediate ASGPR-dependent degradation of PCSK9 and EGFR[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1646198-77-7
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분자량 1528.75
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화학식 C67H121N11O28
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SMILES
C(NC(CCCCCN)=O)(COCCC(NCCCNC(CCCCO[C@H]1[C@H](NC(C)=O)[C@@H](O)[C@@H](O)[C@@H](CO)O1)=O)=O)(COCCC(NCCCNC(CCCCO[C@H]2[C@H](NC(C)=O)[C@@H](O)[C@@H](O)[C@@H](CO)O2)=O)=O)COCCC(NCCCNC(CCCCO[C@H]3[C@H](NC(C)=O)[C@@H](O)[C@@H](O)[C@@H](CO)O3)=O)=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Tri-GalNAc-NH2 Related Classifications
HY-148006 Related Classifications
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