Tri-GalNAc-NH2
Based on 1 Customer Validation
Tri-GalNAc-NH2 is a synthetic tri-N-acetylgalactosamine ligand that targets the asialoglycoprotein receptor (ASGPR). Tri-GalNAc-NH2 can be used as an intermediate for constructing LYTAC antibody-ligand conjugates.
For research use only. We do not sell to patients.
- Purity : 99.85%
- CAS No.: 1646198-77-7
- Formula: C67H121N11O28
- Molecular Weight:1528.75
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Storage:Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Description
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1646198-77-7
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Appearance Oil
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Molecular Weight 1528.75
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Formula C67H121N11O28
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Color Colorless to light yellow
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SMILES
C(NC(CCCCCN)=O)(COCCC(NCCCNC(CCCCO[C@H]1[C@H](NC(C)=O)[C@@H](O)[C@@H](O)[C@@H](CO)O1)=O)=O)(COCCC(NCCCNC(CCCCO[C@H]2[C@H](NC(C)=O)[C@@H](O)[C@@H](O)[C@@H](CO)O2)=O)=O)COCCC(NCCCNC(CCCCO[C@H]3[C@H](NC(C)=O)[C@@H](O)[C@@H](O)[C@@H](CO)O3)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
H2O : 50 mg/mL (32.71 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
Purity & Documentation
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Data Sheet (283 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 0.6541 mL | 3.2706 mL | 6.5413 mL | 16.3532 mL |
| 5 mM | 0.1308 mL | 0.6541 mL | 1.3083 mL | 3.2706 mL | |
| 10 mM | 0.0654 mL | 0.3271 mL | 0.6541 mL | 1.6353 mL | |
| 15 mM | 0.0436 mL | 0.2180 mL | 0.4361 mL | 1.0902 mL | |
| 20 mM | 0.0327 mL | 0.1635 mL | 0.3271 mL | 0.8177 mL | |
| 25 mM | 0.0262 mL | 0.1308 mL | 0.2617 mL | 0.6541 mL | |
| 30 mM | 0.0218 mL | 0.1090 mL | 0.2180 mL | 0.5451 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.