Tribenoside

Cat. No.: HY-108249: FAQs
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Tribenoside is a vasoprotective agent, can be used for the research of hemorrhoids. Tribenoside has mild anti-inflammatory, analgesic, and wound healing properties.

For research use only. We do not sell to patients.

Tribenoside Chemical Structure

CAS No. : 10310-32-4

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Description

Tribenoside is a vasoprotective agent, can be used for the research of hemorrhoids. Tribenoside has mild anti-inflammatory, analgesic, and wound healing properties^[1].

In Vitro

Tribenoside (1 nM-100 µM) exhibits cytotoxic effect against HeLa cells with the EC₅₀ of 13.74 µM^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay^[2]

Cell Line:	HeLa cells
Concentration:	1 nM, 10 nM, 100 nM, 1 µM, 10 µM, 100 µM
Incubation Time:	72 hours
Result:	Reduced HeLa cells viability in a dose-responsive manner.

In Vivo

Tribenoside (oral administration in doses of 500 and 1,200 mg/kg weekly) significantly decreases in the development of osteoporosis^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	male C57 black mice^[3]
Dosage:	500 and 1,200 mg/kg weekly
Administration:	Oral administration
Result:	Led to a significant reduction in the overall arthrotic involvement.

Clinical Trial

Molecular Weight

478.58

Formula

C₂₉H₃₄O₆

CAS No.

10310-32-4

SMILES

O[C@H]([C@H]([C@@H]([C@@H](COCC1=CC=CC=C1)OCC2=CC=CC=C2)O3)OCC4=CC=CC=C4)C3OCC

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Yamato Kikkawa, et al. The influence of Tribenoside on expression and deposition of epidermal laminins in HaCaT cells. Biol Pharm Bull. 2010;33(2):307-10. [Content Brief]

[2]. Yu-Chen Lo, et al. Computational Cell Cycle Profiling of Cancer Cells for Prioritizing FDA-Approved Drugs with Repurposing Potential. Sci Rep. 2017 Sep 12;7(1):11261. [Content Brief]

[3]. G Wilhelmi, et al. Suitability of the C57 black mouse as an experimental animal for the study of skeletal changes due to ageing, with special reference to osteo-arthrosis and its response to tribenoside. Pharmacology. 1976;14(4):289-96. [Content Brief]

Tribenoside Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tribenoside10310-32-4OthersVasoprotective Agenthemorrhoidsanti-inflammatoryanalgesicInhibitorinhibitorinhibit

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