Tris(2-cyanoethyl)phosphine
Based on 1 Customer Validation
Tris (2-cyanoethyl) phosphine is a protein crosslinker. Tris (2-cyanoethyl) phosphine can be used to synthesize copper (I) complexes with anti-tumor activity.
For research use only. We do not sell to patients.
- Purity : 98.0%
- CAS No.: 4023-53-4
- Formula: C9H12N3P
- Molecular Weight:193.19
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Storage:
-20°C, stored under nitrogen, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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(Rac)-BINAPIsomer
Biological Activity
Description
In Vitro
Tris (2-cyanoethyl) phosphine (72 h) alone does not inhibit the growth of tumor cells including HL60, MCF-7, HCT-15, HeLa and A549, with an IC50 value greater than 100 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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CAS No. 4023-53-4
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Appearance Solid
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Molecular Weight 193.19
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Formula C9H12N3P
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Color White to off-white
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SMILES
N#CCCP(CCC#N)CCC#N
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, stored under nitrogen, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)
Solvent & Solubility
In Vitro:
DMSO : ≥ 83.33 mg/mL (431.34 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (480 KB)
- English - EN (480 KB)
- Français - FR (480 KB)
- Deutsch - DE (480 KB)
- Norwegian - NO (480 KB)
- Español - ES (480 KB)
- Swedish - SV (480 KB)
- Italian - IT (480 KB)
- Korean - KR (480 KB)
- Portuguese - PT (480 KB)
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Handling Instructions (2659 KB)
References
[1]. Zanella A, et al. Cytotoxicity in human cancer cells and mitochondrial dysfunction induced by a series of new copper(I) complexes containing tris(2-cyanoethyl)phosphines. Invest New Drugs. 2011;29(6):1213-1223. [Content Brief]
[2].
Zanella A, et, al. Cytotoxicity in human cancer cells and mitochondrial dysfunction induced by a series of new copper(I) complexes containing tris(2-cyanoethyl)phosphines. Invest New Drugs. 2011 Dec;29(6):1213-23.
[Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.1763 mL | 25.8813 mL | 51.7625 mL | 129.4063 mL |
| 5 mM | 1.0353 mL | 5.1763 mL | 10.3525 mL | 25.8813 mL | |
| 10 mM | 0.5176 mL | 2.5881 mL | 5.1763 mL | 12.9406 mL | |
| 15 mM | 0.3451 mL | 1.7254 mL | 3.4508 mL | 8.6271 mL | |
| 20 mM | 0.2588 mL | 1.2941 mL | 2.5881 mL | 6.4703 mL | |
| 25 mM | 0.2071 mL | 1.0353 mL | 2.0705 mL | 5.1763 mL | |
| 30 mM | 0.1725 mL | 0.8627 mL | 1.7254 mL | 4.3135 mL | |
| 40 mM | 0.1294 mL | 0.6470 mL | 1.2941 mL | 3.2352 mL | |
| 50 mM | 0.1035 mL | 0.5176 mL | 1.0353 mL | 2.5881 mL | |
| 60 mM | 0.0863 mL | 0.4314 mL | 0.8627 mL | 2.1568 mL | |
| 80 mM | 0.0647 mL | 0.3235 mL | 0.6470 mL | 1.6176 mL | |
| 100 mM | 0.0518 mL | 0.2588 mL | 0.5176 mL | 1.2941 mL |
Tris(2-cyanoethyl)phosphine Related Classifications
HY-W074006 Related Classifications
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