TRK-IN-29

TRK-IN-29 (Compound B31) is a second-generation TRK inhibitor (IC50: 9 nM, 0.6 nM, 18 nM, 5 nM, 6 nM for TRKAG595R, TRKAF589L, TRKAG667C, TRKA and TRKC respectively). TRK-IN-29 inhibits the phosphorylation of TRKA. TRK-IN-29 has good antiproliferative activities against NTRK fusion positive cells. TRK-IN-29 has exellent plasma stability and moderate pharmacokinetic properties.

For research use only. We do not sell to patients.

  • Formula: C19H17F3N6O
  • Molecular Weight:402.37
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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All Trk Receptor Isoforms

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