Tubulin/PARP-IN-1
Tubulin/PARP-IN-1 (compound 14) is a dual PARP-tubulin inhibitor with activity against endometrial cancer. Tubulin/PARP-IN-1 inhibits PARP and tubulin with IC50s of 74 nM (PARP1), 109 nM (PARP2), and 1.4 μM (Microtubule/Tubulin), respectively. Tubulin/PARP-IN-1 can induce apoptosis and autophagy and cause cell cycle arrest in the G2/M phase.
For research use only. We do not sell to patients.
- Formula: C19H13FO3
- Molecular Weight:308.30
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
IC50: 74 nM (PARP1), 109 nM (PARP2), 1.4 μM (Microtubule/Tubulin)[1]
Chemical Information
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Molecular Weight 308.30
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Formula C19H13FO3
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SMILES
O=C1C=C(OC2=C1C=CC(C3=COC=C3)=C2)C4C=CC(F)=CC4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Tubulin/PARP-IN-1 Related Classifications
HY-157165 Related Classifications
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