2. Cell Cycle/DNA Damage Cytoskeleton
  3. Microtubule/Tubulin
  4. Tubulin polymerization-IN-69

Tubulin polymerization-IN-69 (compund 6c) significantly inhibits microtubule/tubulin polymerization in vitro (78.3% inhibition) with an IC50 value of 6.53 μM, and rapidly induces apoptotic cell death and G2/M cell cycle arrest in MCF-7 cells.

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Tubulin polymerization-IN-69

Tubulin polymerization-IN-69 Estructura química

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Tubulin polymerization-IN-69 Related Antibodies

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Descripciòn

Tubulin polymerization-IN-69 (compund 6c) significantly inhibits microtubule/tubulin polymerization in vitro (78.3% inhibition) with an IC50 value of 6.53 μM, and rapidly induces apoptotic cell death and G2/M cell cycle arrest in MCF-7 cells[1].

IC50 & Target

Microtubule/Tubulin[1]
Peso molecular

531.54

Fòrmula

C25H21N7O5S
SMILES

O=C(C1=C2C=CC=C1)N(CC3=CN(CCC(NC4=CC=C(S(=O)(NC5=NC=CC=C5)=O)C=C4)=O)N=N3)C2=O
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Room temperature in continental US; may vary elsewhere.
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Tubulin polymerization-IN-69 Related Classifications

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Keywords:

Tubulin polymerization-IN-69Microtubule/TubulinInhibitorinhibitorinhibit

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Nombre del producto:
Tubulin polymerization-IN-69
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HY-168128
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