NBD-2
NBD-2 is an inhibitor of the NEMO-IKKα/β interaction in the NF-κB signaling pathway. NBD-2 specifically inhibits the typical NF-κB signaling pathway in vitro and in vivo, reducing the inflammatory response in lipopolysaccharide (LPS) induced acute lung injury (ALI). NBD-2 exhibits significant anti-inflammatory activity. NBD-2 can be used to study diseases related to NF-κB signaling pathway, including autoimmune diseases, cancer, etc.
For research use only. We do not sell to patients.
- Formula: C73H86F8N14O17S2
- Molecular Weight:1647.66
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
-
Molecular Weight 1647.66
-
Formula C73H86F8N14O17S2
-
Sequence
Thr-Ala-Leu-Cys-Trp-Cys-Trp-Leu-Gln-Thr-Glu (Cyclo(Cys4-2(4F-Ph)-Cys6)
-
Sequence Shortening
TALCWCWLQTE (Cyclo(Cys4-2(4F-Ph)-Cys6)
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)