UDP-6-azido-6-Deoxy-D-Glc
UDP-6-azido-6-Deoxy-D-Glc (UDP-α-6N3-glucose) is a UDP-sugar donor. UDP-6-azido-6-Deoxy-D-Glc is used for the selective labeling of 5-hmC in genomic DNA. UDP-6-azido-6-Deoxy-D-Glc enables glyco-diversification modification of saponin intermediates and click chemistry-based derivatization.
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- CAS No.: 537039-67-1
- Formula: C15H23N5O16P2
- Molecular Weight:591.31
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
UDP-6-azido-6-Deoxy-D-Glc (5 mM) can be efficiently utilized by QsFucT for glycosylation of the C28 carboxyl group of TriX-QA, with a conversion rate of 79.9%[2].
UDP-6-azido-6-Deoxy-D-Glc (5 mM) can be efficiently utilized by SvFucT for glycosylation of the C28 carboxyl group of TriX-QA, with a conversion rate of 80.6%[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 537039-67-1
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Molecular Weight 591.31
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Formula C15H23N5O16P2
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SMILES
O=C(C=CN1[C@H]2[C@H](O)[C@H](O)[C@@H](COP(OP(O[C@H]3O[C@H](CN=[N+]=[N-])[C@@H](O)[C@H](O)[C@H]3O)(O)=O)(O)=O)O2)NC1=O
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Synonyms
UDP-α-6N3-glucose; 6-Azidoglucose-UDP
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Wang J, et al. Efficient chemoenzymatic synthesis of UDP-α-6-N3-glucose. Bioorg Med Chem Lett. 2019 May 1;29(9):1148-1151. [Content Brief]
[2]. Hudson GA, et al. Enzymology and Structural Basis of Glycosyltransferases Involved in Saponin C28 Carboxylic Acid ‑d‑Fucosylation. JACS Au. 2025 Dec 22;5(12):6011-6024. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)