D-SNAP
Based on 1 Customer Validation
D-SNAP (S-Nitroso-N-acetylpenicillamine) can Generate nitric oxide and form superoxides spontaneously under physiological conditions and is often used to probe the cell stress response and stimulate calcium-independent synaptic vesicle release.
For research use only. We do not sell to patients.
- Purity: 95.0%
- CAS No.: 79032-48-7
- Formula: C7H12N2O4S
- Molecular Weight:220.25
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Storage:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HT-29 | EC50 |
>1000 μM
Compound: SNAP
|
Apoptosis induction in human HT29 cells after 24 hrs
Apoptosis induction in human HT29 cells after 24 hrs
|
[PMID: 17441704] |
| LLC-MK2 | CC50 |
200 μM
Compound: SNAP
|
Cytotoxicity against monkey LLC-MK2 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
Cytotoxicity against monkey LLC-MK2 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
|
[PMID: 37159959] |
Chemical Information
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CAS No. 79032-48-7
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Appearance Solid
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Molecular Weight 220.25
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Formula C7H12N2O4S
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Color Light green to green
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SMILES
O=NSC(C)(C)[C@H](C(O)=O)NC(C)=O
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Synonyms
S-Nitroso-N-acetylpenicillamine
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
DMSO : ≥ 100 mg/mL (454.03 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (244 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.5403 mL | 22.7015 mL | 45.4030 mL | 113.5074 mL |
| 5 mM | 0.9081 mL | 4.5403 mL | 9.0806 mL | 22.7015 mL | |
| 10 mM | 0.4540 mL | 2.2701 mL | 4.5403 mL | 11.3507 mL | |
| 15 mM | 0.3027 mL | 1.5134 mL | 3.0269 mL | 7.5672 mL | |
| 20 mM | 0.2270 mL | 1.1351 mL | 2.2701 mL | 5.6754 mL | |
| 25 mM | 0.1816 mL | 0.9081 mL | 1.8161 mL | 4.5403 mL | |
| 30 mM | 0.1513 mL | 0.7567 mL | 1.5134 mL | 3.7836 mL | |
| 40 mM | 0.1135 mL | 0.5675 mL | 1.1351 mL | 2.8377 mL | |
| 50 mM | 0.0908 mL | 0.4540 mL | 0.9081 mL | 2.2701 mL | |
| 60 mM | 0.0757 mL | 0.3784 mL | 0.7567 mL | 1.8918 mL | |
| 80 mM | 0.0568 mL | 0.2838 mL | 0.5675 mL | 1.4188 mL | |
| 100 mM | 0.0454 mL | 0.2270 mL | 0.4540 mL | 1.1351 mL |