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KIN-8194

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KIN-8194 is an orally active dual inhibitor of HCK and BTK, with IC50 values of 0.915 and <0.495 nM, respectively. KIN-8194 impairs growth and integrin-mediated adhesion of BTKi-resistant mantle cell lymphoma (MCL). KIN-8194 overcomes ibrutinib (HY-10997) resistance with a survival benefit in TMD-8 ABC DLBCL xenografted mice.

For research use only. We do not sell to patients.

  • Purity: 99.26%
  • CAS No.: 330786-01-1
  • Formula: C28H33N7O
  • Molecular Weight:483.61
  • Storage:
    Powder   -20°C, 3 years , 4°C, 2 years ; In solvent   -80°C, 6 months , -20°C, 1 month
  • KIN-8194 Chemical Structure
    KIN-8194 Chemical Structure
CAS No.: 330786-01-1
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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  • KIN-8194 Chemical Structure
    KIN-8194 Chemical Structure
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  • KIN-8194