Val-Cit-PAB-DEA-Dxd TFA
Based on 1 Customer Validation
Val-Cit-PAB-DEA-Dxd (Compound 81) TFA is a Drug-Linker Conjugates for ADC, which is composed of a linker and a toxic molecule Dxd (HY-13631D). Val-Cit-PAB-DEA-Dxd can be used for ADC synthesis.
For research use only. We do not sell to patients.
- Purity: 99.11%
- Formula: C52H62F4N10O14
- Molecular Weight:1127.10
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Storage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
All Drug-Linker Conjugates for ADC Isoforms
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Biological Activity
Chemical Information
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Appearance Solid
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Molecular Weight 1127.10
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Formula C52H62F4N10O14
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Color Light yellow to yellow
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SMILES
CN(C(OCC1=CC=C(NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)N)=O)=O)C=C1)=O)CCN(C)C(OCC(N[C@@H]2C3=C4C(C(N5C4)=CC([C@](O)(C(OC6)=O)CC)=C6C5=O)=NC7=CC(F)=C(C)C(CC2)=C73)=O)=O.OC(C(F)(F)F)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : ≥ 100 mg/mL (88.72 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.8872 mL | 4.4362 mL | 8.8723 mL | 22.1808 mL |
| 5 mM | 0.1774 mL | 0.8872 mL | 1.7745 mL | 4.4362 mL | |
| 10 mM | 0.0887 mL | 0.4436 mL | 0.8872 mL | 2.2181 mL | |
| 15 mM | 0.0591 mL | 0.2957 mL | 0.5915 mL | 1.4787 mL | |
| 20 mM | 0.0444 mL | 0.2218 mL | 0.4436 mL | 1.1090 mL | |
| 25 mM | 0.0355 mL | 0.1774 mL | 0.3549 mL | 0.8872 mL | |
| 30 mM | 0.0296 mL | 0.1479 mL | 0.2957 mL | 0.7394 mL | |
| 40 mM | 0.0222 mL | 0.1109 mL | 0.2218 mL | 0.5545 mL | |
| 50 mM | 0.0177 mL | 0.0887 mL | 0.1774 mL | 0.4436 mL | |
| 60 mM | 0.0148 mL | 0.0739 mL | 0.1479 mL | 0.3697 mL | |
| 80 mM | 0.0111 mL | 0.0555 mL | 0.1109 mL | 0.2773 mL |